Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL29085274 | 1.00 | LMNA (0.64) | LMNAALDH1A1THRBMAPTATM | |
| Glycerin SCHEMBL1171535 | 1.00 | LMNA (0.64) | LMNAALDH1A1THRBMAPTATM | |
| Glycerin SCHEMBL830352 | 1.00 | — | — | |
| Glycerin SCHEMBL29085267 | 1.00 | LMNA (0.64) | LMNAALDH1A1THRBMAPTATM | |
| Dioxane SCHEMBL1291894 | 0.97 | LMNA (0.60) | LMNAALDH1A1THRBMAPTATM | |
| Dioxane SCHEMBL28308269 | 0.97 | LMNA (0.60) | LMNAALDH1A1THRBMAPTATM | |
| Glycerin SCHEMBL2046780 | 0.91 | LMNA (0.53) | LMNAALDH1A1THRBMAPTATM | |
| Glycerin SCHEMBL28000527 | 0.91 | LMNA (0.53) | LMNAALDH1A1THRBMAPTATM | |
| Glycerin SCHEMBL28749776 | 0.90 | LMNA (0.60) | LMNAALDH1A1THRBMAPTATM | |
| Glycerin SCHEMBL10659943 | 0.88 | ALDH1A1 (0.50) | LMNAALDH1A1THRBMAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049864-A2 | NEW FILL COMPOSITIONS AND METHOD FOR MAKING THE SAME | Dow Global Technologies Inc. (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2008094195-A2 | NEW FILL COMPOSITIONS AND METHOD FOR MAKING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-08-07 | — | — | WO | disclosed |