Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800695 | 0.79 | GAA (0.58) | GAAHTTKMT2AKDM4EPOLB | |
| SCHEMBL8372879 | 0.72 | GAA (0.36) | GAAHTTPOLBRECQLTSHR | |
| SCHEMBL6559770 | 0.72 | POLB (0.33) | GAAHTTPOLBRECQLTSHR | |
| SCHEMBL13195454 | 0.70 | — | — | |
| SCHEMBL2025665 | 0.68 | MAOB (0.33) | — | |
| SCHEMBL11799986 | 0.68 | GAA (0.40) | GAAKMT2AKDM4E | |
| SCHEMBL28628206 | 0.67 | — | — | |
| SCHEMBL28628207 | 0.66 | — | — | |
| SCHEMBL1933227 | 0.63 | MAOB (0.48) | GAAHTTKMT2AKDM4E | |
| SCHEMBL1933229 | 0.63 | GAA (0.47) | GAAHTTKMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10478513-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | THE REGENTS OF THE UNIVERSITY OF CALIFONIA (US) | 2019-11-19 | — | — | US | disclosed |
| US-20180221514-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10478513-B2 | Nitroxide containing amyloid binding agents for imaging and therapeutic uses | APP, APBA1, CRYAB | GAA 1175/4885HTT 55/4885KMT2A 4406/4885 |
| US-20180221514-A1 | NITROXIDE CONTAINING AMYLOID BINDING AGENTS FOR IMAGING AND THERAPEUTIC USES | APP, APBA1, CRYAB | GAA 1049/4885HTT 53/4885KMT2A 4490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.