SCHEMBL6559770

SCHEMBL6559770

C=C(C)C(=O)NC1CC(C)(C)NC1(C)C

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.33
GAA P10253 2/20 0.32
RECQL P46063 1/20 0.32
EZH2 Q15910 2/20 0.31
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 2/20 0.30
ATM Q13315 1/20 0.30
HSD17B10 Q99714 1/20 0.30
HTT P42858 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109129 0.79 RECQL (0.49) POLBGAARECQLEZH2ALDH1A1
Hydrochloric Acid SCHEMBL10719974 0.77 RECQL (0.47) POLBGAARECQLEZH2ALDH1A1
SCHEMBL8372879 0.76 GAA (0.36) POLBGAARECQLEZH2TSHR
SCHEMBL20467916 0.72 GAA (0.38) POLBGAARECQLEZH2TSHR
SCHEMBL4552228 0.66 ALDH1A1 (0.33) GAAALDH1A1L3MBTL1ATM
SCHEMBL6750789 0.64 GAA (0.34) POLBGAARECQLEZH2ALDH1A1
SCHEMBL12198708 0.64
SCHEMBL10578940 0.63 KDM4E (0.32) GAA
SCHEMBL3295977 0.63 RECQL (0.57) POLBGAARECQLEZH2ALDH1A1
SCHEMBL10457142 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1999064563-A1 POLYMER CARRIER FOR CULTIVATION OF KERATINOCYTES ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) 1999-12-16 WO claimed
EP-1058698-B1 PREPARATION FOR PREVENTION AND HEALING OF INFLAMMATION AFFECTIONS USTAV MAKROMOLEKULARNI CHEMIE (CZ) 2004-07-28 EP disclosed
US-6610284-B1 Derivatives of sterically hindered amines selected from the group consisting of: soluble polymers or copolymers prepared by radical polymerization in the presence of 0.01 to 10% by weight, of initiators prepared:in a polymerization mixture INSTITUTE OF MACROMOLECULAR CHEMISTRY (CZ) 2003-08-26 US disclosed
EP-1058698-A1 PREPARATION FOR PREVENTION AND HEALING OF INFLAMMATION AFFECTIONS USTAV MAKROMOLEKULARNI CHEMIE AKADEMIE VED CESKE REPUBLIKY (CZ) 2000-12-13 EP disclosed
WO-1999064563-A1 POLYMER CARRIER FOR CULTIVATION OF KERATINOCYTES ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VĚD ČESKÉ REPUBLIKY (CZ) 1999-12-16 WO disclosed
WO-1999028359-A1 PREPARATION FOR PREVENTION AND HEALING OF INFLAMMATION AFFECTIONS ÚSTAV MAKROMOLEKULÁRNÍ CHEMIE AKADEMIE VED C^¿ESKÉ REPUBLIKY (CZ) 1999-06-10 WO disclosed