SCHEMBL2046809

SCHEMBL2046809

c1ccc(C(CCCC(=NO[Si](c2ccccc2)(c2ccccc2)c2ccccc2)c2ccccc2)=NO[Si](c2ccccc2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 7/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
ATM Q13315 1/20 0.36
PPARG P37231 6/20 0.35
DRD4 P21917 4/20 0.33
TBXA2R P21731 4/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
DRD2 P14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2046807 1.00 PPARA (0.38) PPARAL3MBTL1GAAMAPTATM
SCHEMBL2050834 0.93 PPARA (0.40) PPARAL3MBTL1GAAMAPTATM
SCHEMBL2050836 0.93 PPARA (0.40) PPARAL3MBTL1GAAMAPTATM
SCHEMBL9898975 0.91 L3MBTL1 (0.49) PPARAL3MBTL1GAAMAPTLMNA
SCHEMBL9898977 0.91 L3MBTL1 (0.49) PPARAL3MBTL1GAAMAPTLMNA
SCHEMBL2047077 0.84 PPARA (0.42) PPARAL3MBTL1GAAMAPTATM
SCHEMBL2047076 0.84 PPARA (0.42) PPARAL3MBTL1GAAMAPTATM
SCHEMBL9898979 0.84 NR4A2 (0.47) PPARAL3MBTL1GAAMAPTPPARG
SCHEMBL2047973 0.84 PPARA (0.41) PPARAL3MBTL1MAPTATMPPARG
SCHEMBL2047974 0.84 PPARA (0.41) PPARAL3MBTL1MAPTATMPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP disclosed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed