Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8692979 | 1.00 | ALDH1A1 (0.57) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL21349634 | 1.00 | ALDH1A1 (0.57) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL4088388 | 0.97 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL23561000 | 0.97 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL23352964 | 0.97 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL23221351 | 0.97 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL13007137 | 0.97 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL18900975 | 0.97 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL8840602 | 0.97 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL69669 | 0.97 | ALDH1A1 (0.53) | ALDH1A1THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040178-A1 | Single-Chain Trail-Receptor Agonist Proteins | ABBVIE INC. | 2021-02-11 | — | — | US | disclosed |
| US-20180222962-A1 | Single-Chain Trail-Receptor Agonist Proteins | ABBVIE INC (US) | 2018-08-09 | — | — | US | disclosed |