Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF20A | O95235 | 2/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.56 |
| ▸ | TUBB | P07437 | 3/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.56 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.56 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.56 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.56 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20468563 | 0.88 | KIF20A (0.57) | KIF20ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16190121 | 0.87 | KIF20A (0.67) | KIF20AAPPPOLBNQO2MEN1 | |
| SCHEMBL17556118 | 0.87 | KIF20A (0.67) | KIF20AAPPPOLBNQO2MEN1 | |
| SCHEMBL11657765 | 0.81 | KIF20A (0.71) | KIF20AAPPPOLBMEN1NPC1 | |
| SCHEMBL6823782 | 0.79 | TUBB1 (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6823793 | 0.79 | TUBB1 (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31238100 | 0.79 | TUBB1 (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7823509 | 0.79 | TUBB1 (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7823504 | 0.79 | TUBB1 (0.74) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6823787 | 0.79 | TUBB1 (0.59) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144910-A1 | METHODS OF PROTECTING AGAINST NEURODEGENERATION | BIOVENTURES, LLC (US) | 2018-08-09 | — | — | WO | disclosed |