Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF20A | O95235 | 2/20 | 0.57 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20468569 | 0.88 | KIF20A (0.57) | KIF20AAPPPOLBMEN1KMT2A | |
| SCHEMBL17556118 | 0.84 | KIF20A (0.67) | KIF20AAPPPOLBMEN1KMT2A | |
| SCHEMBL16190121 | 0.84 | KIF20A (0.67) | KIF20AAPPPOLBMEN1KMT2A | |
| SCHEMBL11657765 | 0.84 | KIF20A (0.71) | KIF20AAPPPOLBMEN1KMT2A | |
| SCHEMBL5613888 | 0.80 | KDM4E (0.49) | MEN1KMT2AALDH1A1MAPTRECQL | |
| SCHEMBL5613889 | 0.80 | KDM4E (0.49) | MEN1KMT2AALDH1A1MAPTRECQL | |
| SCHEMBL22950670 | 0.79 | TUBB4A (0.59) | POLBMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL30734311 | 0.79 | TUBB4A (0.59) | POLBMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL30734337 | 0.79 | TUBB4A (0.59) | POLBMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL1959686 | 0.79 | PDE4B (0.46) | MAPTRECQLHIF1ASMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018144910-A1 | METHODS OF PROTECTING AGAINST NEURODEGENERATION | BIOVENTURES, LLC (US) | 2018-08-09 | — | — | WO | disclosed |