Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | CACNB1 | Q02641 | 2/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20469792 | 1.00 | CETP (0.40) | CETPNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL23542112 | 0.90 | MGLL (0.46) | CETPNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL20469661 | 0.90 | MGLL (0.46) | CETPNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL20469656 | 0.89 | CACNA2D1 (0.40) | CETPMEN1KMT2AALDH1A1CTSA | |
| SCHEMBL20469761 | 0.89 | CETP (0.42) | CETPNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL20469753 | 0.89 | CETP (0.42) | CETPNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL20469805 | 0.89 | KMT2A (0.44) | CETPNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL20469662 | 0.89 | ABL1 (0.41) | CETPNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL20469799 | 0.88 | SMN1; SMN2 (0.40) | CETPNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL20469659 | 0.88 | CTSA (0.41) | CETPNPSR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11040963-B2 | Piperazine derivatives for influenza virus inhibitions | JANSSEN VACCINES & PREVENTION B.V. (NL) | 2021-06-22 | — | — | US | disclosed |
| WO-2018141854-A1 | PIPERAZINE DERIVATIVES FOR INFLUENZA VIRUS INHIBITION | JANSSEN VACCINES & PREVENTION B.V. (NL) | 2018-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040963-B2 | Piperazine derivatives for influenza virus inhibitions | HAVCR2, BAZ2A, MAVS | CETP 2633/4885NPSR1 748/4885MEN1 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.