Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 5/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.33 |
| ▸ | ITGAL | P20701 | 5/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24758455 | 0.85 | HTR2A (0.47) | HTR2AHTR2CHTR2BCYP1A2PDE10A | |
| SCHEMBL22179531 | 0.85 | MEN1 (0.37) | HTR2AHTR2CHTR2BCYP1A2PDE10A | |
| SCHEMBL23939714 | 0.82 | HTR2A (0.40) | HTR2AHTR2CHTR2BCYP1A2ACACB | |
| SCHEMBL21282994 | 0.82 | CYP1A2 (0.37) | HTR2AHTR2CHTR2BCYP1A2PDE10A | |
| SCHEMBL25728286 | 0.78 | HTR2A (0.47) | HTR2AHTR2CHTR2BCYP1A2ADRB2 | |
| SCHEMBL25098855 | 0.77 | AKT1 (0.40) | HTR2AHTR2CHTR2BPDE10AGRM4 | |
| SCHEMBL23841158 | 0.75 | HTR2A (0.38) | HTR2AHTR2CHTR2BCYP1A2PDE10A | |
| SCHEMBL23008292 | 0.74 | HTR2A (0.42) | HTR2AHTR2CHTR2BCYP1A2PDE10A | |
| SCHEMBL21282890 | 0.73 | HTR2A (0.35) | HTR2AHTR2CHTR2BCYP1A2PDE10A | |
| SCHEMBL21880734 | 0.73 | MET (0.41) | PDE10AACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220394973-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-12-15 | — | — | US | disclosed |
| US-10954340-B2 | Polyimide precursor composition | TOKYO OHKA KOGYO CO., LTD. (JP) | 2021-03-23 | — | — | US | disclosed |
| US-10696845-B2 | Energy-sensitive resin composition | TOKYO OHKA KOGYO CO., LTD. (JP) | 2020-06-30 | — | — | US | disclosed |
| US-20190225804-A1 | ENERGY-SENSITIVE RESIN COMPOSITION | TOKYO OHKA KOGYO CO., LTD. (JP) | 2019-07-25 | — | — | US | disclosed |
| US-20180223045-A1 | POLYIMIDE PRECURSOR COMPOSITION | TOKYO OHKA KOGYO CO., LTD. (JP) | 2018-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220394973-A1 | ANTI-FUNGALS COMPOUNDS TARGETING THE SYNTHESIS OF FUNGAL SPHINGOLIPIDS | ERG28, UGCG, DPM1 | HTR2A 4490/4885HTR2C 4546/4885HTR2B 4756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.