Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7743268 | 0.83 | TSHR (0.61) | TSHRKDM4EPOLBCA1CA2 | |
| SCHEMBL7427600 | 0.80 | TSHR (0.47) | TSHRKDM4EPOLBCA1CA2 | |
| SCHEMBL7427597 | 0.80 | TSHR (0.47) | TSHRKDM4EPOLBCA1CA2 | |
| SCHEMBL203767 | 0.79 | TSHR (0.56) | TSHRKDM4EPOLBIDO1NPC1 | |
| SCHEMBL7884716 | 0.79 | TSHR (0.56) | TSHRKDM4EPOLBCA1CA2 | |
| Hydrochloric Acid SCHEMBL8328150 | 0.78 | TSHR (0.54) | TSHRKDM4EPOLBCA1CA2 | |
| SCHEMBL2080921 | 0.77 | TSHR (0.48) | TSHRKDM4EPOLBCA1CA2 | |
| Hydroxyamine SCHEMBL1680424 | 0.77 | TSHR (0.83) | TSHRKDM4EPOLBCA1CA2 | |
| Hydrogen Peroxide SCHEMBL28758135 | 0.77 | TSHR (0.94) | TSHRKDM4EPOLBCA1CA2 | |
| Carbamic Acid SCHEMBL119806 | 0.76 | TSHR (0.71) | TSHRKDM4EPOLBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250179008-A1 | ANTIBACTERIAL AGENTS | TAXIS PHARMACEUTICALS, INC. (US) | 2025-06-05 | — | — | US | disclosed |
| US-20150191420-A1 | ANTIBACTERIAL AGENTS | TAXIS PHARMACEUTICALS, INC. | 2015-07-09 | — | — | US | disclosed |
| US-8865736-B2 | Antibacterial agents | Biota Scientific Pty Ltd (AU) | 2014-10-21 | — | — | US | disclosed |
| WO-2014018807-A1 | PEPTIDE EPOXYKETONE COMPOUNDS | CENTRAX INTERNATIONAL, INC. (US) | 2014-01-30 | — | — | WO | disclosed |
| CN-102008459-B | Antibacterial agents | BIOTA SCIENT MAN | 2013-05-29 | — | — | CN | disclosed |
| US-20130072520-A2 | ANTIBACTERIAL AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2013-03-21 | — | — | US | disclosed |
| US-20120122918-A1 | ANTIBACTERIAL AGENTS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-05-17 | — | — | US | disclosed |
| US-8088791-B2 | Antibacterial agents | Biots Scientific Management Pty Ltd (AU) | 2012-01-03 | — | — | US | disclosed |
| CN-101404989-B | Antibacterial agent | PROLYSIS LTD | 2011-10-05 | — | — | CN | disclosed |
| EP-1996180-B1 | BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD (GB) | 2011-08-03 | — | — | EP | disclosed |
| US-20100173933-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2010-07-08 | — | — | US | disclosed |
| CN-101404989-A | Antibacterial agent | PROLYSIS LTD (GB) | 2009-04-08 | — | — | CN | disclosed |
| EP-1996180-A1 | ANTIBACTERIAL AGENTS | Prolysis Limited (GB) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107758-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2007-09-27 | — | — | WO | disclosed |
| US-RE39576-E1 | Enzyme inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-17 | — | — | US | disclosed |
| CN-1070849-C | Enzyme inhibitors | WELLCOME FOUND (GB) | 2001-09-12 | — | — | CN | disclosed |
| US-5889056-A | OF NITRIC OXIDE SYNTHASE; HYPOTENSIVE AGENT, ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | GLAXO WELLSOME INC. (US) | 1999-03-30 | — | — | US | disclosed |
| CN-1155276-A | Enzyme inhibitors | WELLCOME FOUND (GB) | 1997-07-23 | — | — | CN | disclosed |
| EP-0765308-A1 | ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1997-04-02 | — | — | EP | disclosed |
| WO-1995034534-A1 | ENZYME INHIBITORS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122918-A1 | ANTIBACTERIAL AGENTS | ALK, ROS1, ARG1 | TSHR 816/4885KDM4E 819/4885POLB 445/4885 |
| US-20130072520-A2 | ANTIBACTERIAL AGENTS | ALK, ROS1, NOX1 | TSHR 1283/4885KDM4E 2407/4885POLB 364/4885 |
| US-20150191420-A1 | ANTIBACTERIAL AGENTS | ALK, ARG1, ROS1 | TSHR 844/4885KDM4E 1251/4885POLB 435/4885 |
| US-20250179008-A1 | ANTIBACTERIAL AGENTS | ALK, ROS1, NOX1 | TSHR 1283/4885KDM4E 2407/4885POLB 364/4885 |
| US-20100173933-A1 | ANTIBACTERIAL AGENTS | ALK, ROS1, NOX1 | TSHR 1283/4885KDM4E 2407/4885POLB 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.