Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.51 |
| ▸ | AGXT | P21549 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL28054623 | 0.95 | TSHR (0.71) | TSHRALDH1A1PARP10IDO1KMT2A | |
| Hydroxyamine SCHEMBL1680424 | 0.87 | TSHR (0.83) | TSHRALDH1A1IDO1MAPK1L3MBTL1 | |
| Benzyl Carbamate SCHEMBL7386720 | 0.87 | TSHR (0.60) | TSHRALDH1A1PARP10KMT2AMAPK1 | |
| Hydrogen Peroxide SCHEMBL28758135 | 0.87 | TSHR (0.94) | TSHRALDH1A1IDO1KMT2AMAPK1 | |
| Acetone SCHEMBL28740549 | 0.86 | TSHR (0.71) | TSHRALDH1A1KMT2AMAPK1L3MBTL1 | |
| Acetic Acid SCHEMBL28710458 | 0.86 | TSHR (0.71) | TSHRALDH1A1KMT2AMAPK1L3MBTL1 | |
| Acetic Acid SCHEMBL4466285 | 0.86 | TSHR (0.71) | TSHRALDH1A1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL203767 | 0.85 | TSHR (0.56) | TSHRALDH1A1PARP10IDO1KMT2A | |
| SCHEMBL27380 | 0.84 | TSHR (1.00) | TSHRALDH1A1IDO1SLC6A2SLC6A3 | |
| SCHEMBL5311581 | 0.84 | TSHR (1.00) | TSHRALDH1A1IDO1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220031852-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2022-02-03 | — | — | US | disclosed |
| US-20200360521-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2020-11-19 | — | — | US | disclosed |
| US-9919060-B2 | Treatment or prophylaxis of proliferative conditions | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2018-03-20 | — | — | US | disclosed |
| US-20170368188-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2017-12-28 | — | — | US | disclosed |
| EP-2857018-A1 | Treatment or prophylaxis of proliferative conditions | University Court of The University of Dundee (GB) | 2015-04-08 | — | — | EP | disclosed |
| US-20150011512-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2015-01-08 | — | — | US | disclosed |
| US-20120302748-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | THE UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2012-11-29 | — | — | US | disclosed |
| US-8283340-B2 | Treatment or prophylaxis of proliferative conditions | The University of the University of Dundee (GB) | 2012-10-09 | — | — | US | disclosed |
| US-20120190639-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2012-07-26 | — | — | US | disclosed |
| CN-102458394-A | Treatment or prevention of proliferative conditions | UNIV DUNDEE | 2012-05-16 | — | — | CN | disclosed |
| US-20100305070-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | THE UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-12-02 | — | — | US | disclosed |
| WO-2010125350-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-11-04 | — | — | WO | disclosed |
| US-7102023-B2 | Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-09-05 | — | — | US | disclosed |
| US-20040220389-A1 | Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-11-04 | — | — | US | disclosed |
| US-6693178-B2 | HALOGENATED BENZYL ETHER GALACTOPYRANOSIDE, GLUCOPYRANOSIDE, RIBOFURANOSIDE OR XYLOFURANOSIDE DERIVATIVES; STABLE, EASILY REMOVED | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-02-17 | — | — | US | disclosed |
| US-20030181690-A1 | Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-09-25 | — | — | US | disclosed |
| EP-1233970-A2 | PROTECTING GROUPS USEFUL IN THE SYNTHESIS OF POLYSACCHARIDES, NATURAL PRODUCTS, AND COMBINATORIAL LIBRARIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6426421-B1 | HALOGENATED BENZYL ETHER-BASED PROTECTING GROUPS FOR FUNCTIONAL GROUPS, OF ALCOHOLS, THIOLS, AMINES, CARBOXYLIC ACIDS, AND PHOSPHORIC ACIDS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2002-07-30 | — | — | US | disclosed |
| WO-2001038337-A2 | PROTECTING GROUPS USEFUL IN THE SYNTHESIS OF POLYSACCHARIDES, NATURAL PRODUCTS, AND COMBINATORIAL LIBRARIES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2001-05-31 | — | — | WO | disclosed |
| US-4820718-A | PLATELET ACTIVATING FACTOR INHIBITORS | SANDOZ PHARM. CORP. (US) | 1989-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305070-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | BRCA1, CYP1B1, UGT1A1 | TSHR 3996/4885ALDH1A1 35/4885PARP10 2267/4885 |
| US-20200360521-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | CYP1B1, UGT1A1, CYP1A1 | TSHR 4019/4885ALDH1A1 55/4885PARP10 1723/4885 |
| US-20040220389-A1 | Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries | FUT5, FUT6, UGCG | TSHR 2453/4885ALDH1A1 1137/4885PARP10 945/4885 |
| US-20120302748-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | BRCA1, CYP1B1, UGT1A1 | TSHR 3996/4885ALDH1A1 35/4885PARP10 2267/4885 |
| US-20120190639-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | CYP1B1, UGT1A1, CYP1A1 | TSHR 4019/4885ALDH1A1 55/4885PARP10 1723/4885 |
| US-20220031852-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | CYP1B1, UGT1A1, CYP1A1 | TSHR 4019/4885ALDH1A1 55/4885PARP10 1723/4885 |
| US-20030181690-A1 | Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries | FUT5, FUT6, UGCG | TSHR 2453/4885ALDH1A1 1137/4885PARP10 945/4885 |
| US-20170368188-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | CYP1B1, UGT1A1, CYP1A1 | TSHR 3989/4885ALDH1A1 61/4885PARP10 1447/4885 |
| US-20150011512-A1 | TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS | CYP1B1, UGT1A1, CYP1A1 | TSHR 4019/4885ALDH1A1 55/4885PARP10 1723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.