Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 5/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | STK33 | Q9BYT3 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20463389 | 0.83 | PIK3C3 (0.46) | GRM4KITPIK3C3FFAR1TLR7 | |
| SCHEMBL29890655 | 0.83 | NPC1 (0.45) | KITFFAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20455626 | 0.83 | NPC1 (0.45) | KITFFAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29892155 | 0.83 | KIT (0.46) | KITPIK3C3FFAR1NPC1RAB9A | |
| SCHEMBL22829293 | 0.83 | KIT (0.46) | KITPIK3C3FFAR1NPC1RAB9A | |
| SCHEMBL20470675 | 0.82 | ALDH1A1 (0.46) | KITNPC1RAB9ASMN1; SMN2STK33 | |
| SCHEMBL21629662 | 0.82 | GRM4 (0.57) | GRM4KITFFAR1NPC1RAB9A | |
| SCHEMBL20470566 | 0.82 | KIT (0.43) | KITPIK3C3FFAR1CTNNB1WNT3A | |
| SCHEMBL21657818 | 0.81 | KIT (0.46) | KITPIK3C3FFAR1HDAC3HDAC7 | |
| SCHEMBL29890825 | 0.81 | SCN10A (0.52) | KITPIK3C3FFAR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110248940-B | Aryl hydrocarbon receptor (AhR) modulator compounds | 菲尼克斯药品股份公司 | 2022-07-01 | — | — | CN | disclosed |
| US-10981908-B2 | Aryl hydrocarbon receptor (AHR) modulator compounds | PHENEX PHARMACEUTICALS AG (DE) | 2021-04-20 | — | — | US | disclosed |
| US-10981908-B2 | Aryl hydrocarbon receptor (AHR) modulator compounds | PHENEX PHARMACEUTICALS AG (DE) | 2021-04-20 | — | — | US | disclosed |
| EP-3577112-B1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-12-30 | — | — | EP | disclosed |
| WO-2018141857-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2018-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981908-B2 | Aryl hydrocarbon receptor (AHR) modulator compounds | AHR, ARNT, NR1H2 | GRM4 1712/4885KIT 2587/4885PIK3C3 3889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.