Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PEPD | P12955 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5087041 | 0.80 | ATM (0.52) | ATMPEPDCTSKRENACE | |
| SCHEMBL26980895 | 0.80 | ATM (0.52) | ATMPEPDCTSKRENACE | |
| SCHEMBL26118721 | 0.80 | ATM (0.52) | ATMPEPDCTSKRENACE | |
| SCHEMBL26980896 | 0.80 | ATM (0.52) | ATMPEPDCTSKRENACE | |
| SCHEMBL6126706 | 0.80 | ATM (0.52) | ATMPEPDCTSKRENACE | |
| SCHEMBL10283713 | 0.79 | ATM (0.71) | ATMPEPDCTSK | |
| SCHEMBL16748604 | 0.79 | ATM (0.71) | ATMPEPDCTSK | |
| SCHEMBL19075572 | 0.74 | ATM (0.46) | ATMPEPDCTSK | |
| SCHEMBL19075564 | 0.74 | ATM (0.46) | ATMPEPDCTSK | |
| SCHEMBL26566934 | 0.73 | ATM (0.44) | ATMPEPDCTSKACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180237421-A1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS | VERSEON INTERNATIONAL CORPORATION | 2018-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180237421-A1 | SUBSTITUTED PYRAZOLE COMPOUNDS AS SERINE PROTEASE INHIBITORS | SPINT2, PRSS1, SERPINE1 | ATM 306/4885MEN1 1150/4885KMT2A 1728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.