Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20474259 | 1.00 | KMT2A (0.52) | KMT2ANFE2L2MAPTMEN1RAB9A | |
| SCHEMBL20474218 | 0.89 | KMT2A (0.49) | KMT2ANFE2L2MAPTMEN1RAB9A | |
| SCHEMBL20474221 | 0.89 | KMT2A (0.49) | KMT2ANFE2L2MAPTMEN1RAB9A | |
| SCHEMBL6891543 | 0.78 | KMT2A (0.55) | KMT2AMEN1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6546334 | 0.77 | NFE2L2 (0.55) | KMT2ANFE2L2MAPTMEN1RAB9A | |
| SCHEMBL17967377 | 0.76 | ALDH1A1 (0.61) | MAPTRAB9AALDH1A1NPSR1DHODH | |
| SCHEMBL17967375 | 0.76 | ALDH1A1 (0.61) | MAPTRAB9AALDH1A1NPSR1DHODH | |
| SCHEMBL17967365 | 0.74 | NFE2L2 (0.42) | KMT2ANFE2L2MAPTMEN1RAB9A | |
| SCHEMBL17967366 | 0.74 | NFE2L2 (0.42) | KMT2ANFE2L2MAPTMEN1RAB9A | |
| SCHEMBL12021288 | 0.72 | SMN1; SMN2 (0.53) | KMT2ARAB9AALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10227355-B2 | Quinoline derivatives and preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2019-03-12 | — | — | US | disclosed |
| US-20180237448-A1 | NOVEL QUINOLINE DERIVATIVES AND PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180237448-A1 | NOVEL QUINOLINE DERIVATIVES AND PREPARATION THEREOF | ABL1, FLT3, MAP3K7 | KMT2A 813/4885NFE2L2 623/4885MAPT 2812/4885 |
| US-10227355-B2 | Quinoline derivatives and preparation thereof | ABL1, FLT3, MAP3K7 | KMT2A 870/4885NFE2L2 736/4885MAPT 2415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.