Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKAR | P32238 | 5/20 | 0.44 |
| ▸ | CCKBR | P32239 | 5/20 | 0.44 |
| ▸ | CBLB | Q13191 | 10/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18395704 | 0.91 | CBLB (0.45) | CCKARCCKBRCBLB | |
| SCHEMBL22440664 | 0.85 | CCKBR (0.49) | CCKARCCKBRALDH1A1 | |
| SCHEMBL20474812 | 0.82 | CCKBR (0.55) | CCKARCCKBRCBLB | |
| SCHEMBL20474811 | 0.82 | CCKBR (0.55) | CCKARCCKBRCBLB | |
| SCHEMBL20580593 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1HPGD | |
| SCHEMBL20867031 | 0.79 | CCKAR (0.50) | CCKARCCKBRCBLB | |
| SCHEMBL20867088 | 0.79 | CCKAR (0.50) | CCKARCCKBRCBLB | |
| SCHEMBL18394376 | 0.78 | CBLB (0.47) | CCKARCCKBRCBLB | |
| SCHEMBL20098670 | 0.78 | CCKAR (0.51) | CCKARCCKBRCBLB | |
| SCHEMBL24611903 | 0.76 | CBLB (0.41) | CCKARCCKBRCBLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3582784-B1 | PROCESSES FOR THE PREPARATION OF BENZODIAZEPINE DERIVATIVES | ENANTA PHARM INC (US) | 2022-06-08 | — | — | EP | disclosed |
| US-10906895-B2 | Processes for the preparation of benzodiazepine derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2021-02-02 | — | — | US | disclosed |
| US-20190308964-A1 | PROCESSES FOR THE PREPARATION OF BENZODIAZEPINE DERIVATIVES | ENANTA PHARM INC (US) | 2019-10-10 | — | — | US | disclosed |
| US-10358441-B2 | Processes for the preparation of benzodiazepine derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2019-07-23 | — | — | US | disclosed |
| US-20180237425-A1 | PROCESSES FOR THE PREPARATION OF BENZODIAZEPINE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. | 2018-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180237425-A1 | PROCESSES FOR THE PREPARATION OF BENZODIAZEPINE DERIVATIVES | CYP11B1, CYP11B2, CYP3A5 | CCKAR 711/4885CCKBR 528/4885CBLB 3282/4885 |
| US-10906895-B2 | Processes for the preparation of benzodiazepine derivatives | CYP11B1, CYP11B2, CYP3A5 | CCKAR 711/4885CCKBR 528/4885CBLB 3282/4885 |
| US-10358441-B2 | Processes for the preparation of benzodiazepine derivatives | CYP11B1, CYP11B2, CYP3A5 | CCKAR 711/4885CCKBR 528/4885CBLB 3282/4885 |
| US-20190308964-A1 | PROCESSES FOR THE PREPARATION OF BENZODIAZEPINE DERIVATIVES | CYP11B1, CYP11B2, CYP3A5 | CCKAR 711/4885CCKBR 528/4885CBLB 3282/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.