Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20475249 | 0.81 | NQO2 (0.64) | NQO2KMT2ATP53TDP1KDM4E | |
| SCHEMBL20475271 | 0.79 | NQO2 (0.59) | NQO2KMT2ATP53TDP1KDM4E | |
| SCHEMBL20475523 | 0.79 | NQO2 (0.70) | NQO2KDM4ELMNAPRNPNPSR1 | |
| SCHEMBL13271194 | 0.78 | NQO2 (0.58) | NQO2KMT2AOPRK1LMNAPRNP | |
| SCHEMBL13439503 | 0.77 | NQO2 (0.72) | NQO2KMT2AOPRK1LMNAPRNP | |
| SCHEMBL13313371 | 0.77 | NQO2 (0.72) | NQO2KMT2AOPRK1LMNAPRNP | |
| SCHEMBL18387358 | 0.76 | NQO2 (0.71) | NQO2KMT2AKDM4ELMNAPRNP | |
| SCHEMBL20475263 | 0.76 | ACHE (0.62) | NQO2KMT2AOPRK1KDM4ELMNA | |
| SCHEMBL16862371 | 0.72 | NQO2 (1.00) | NQO2KMT2ANPSR1ACHERAB9A | |
| SCHEMBL18387458 | 0.71 | NQO2 (0.65) | NQO2KMT2AKDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053205-B2 | Phenazine derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-07-06 | — | — | US | disclosed |
| US-11053205-B2 | Phenazine derivatives as antimicrobial agents | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-07-06 | — | — | US | disclosed |
| WO-2018152436-A1 | PHENAZINE DERIVATIVES AS ANTIMICROBIAL AGENTS | UNIVERSITY OF RESEARCH FOUNDATION, INCORPORATED (US) | 2018-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11053205-B2 | Phenazine derivatives as antimicrobial agents | ROS1, NOX4, PRDX3 | NQO2 172/4885KMT2A 3688/4885OPRK1 3086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.