Biphenyl

Biphenyl

SCHEMBL2047569

CCOC(=O)C(CC)P(=O)(O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
ALDH1A1 P00352 2/20 0.52
TSHR P16473 2/20 0.52
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
PIN1 Q13526 1/20 0.45
NPC1 O15118 2/20 0.44
ACP3 P15309 2/20 0.42
MMP8 P22894 1/20 0.42
MAPT P10636 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL829655 0.84 CYP2D6 (0.44) POLBALDH1A1TSHRMMP8LMNA
Butane SCHEMBL2052354 0.81 POLB (0.44) POLBALDH1A1TSHRLMNAGAA
Biphenyl SCHEMBL2044408 0.77 MEN1 (0.51) POLBALDH1A1TSHRMEN1KMT2A
Oxirane SCHEMBL4333005 0.76 TSHR (0.42) POLBALDH1A1TSHRKMT2AMAPT
SCHEMBL1409033 0.73 MMP8 (0.51) POLBALDH1A1TSHRMEN1KMT2A
SCHEMBL2991456 0.73 POLB (0.42) POLBALDH1A1TSHRMMP8LMNA
Biphenyl SCHEMBL5571790 0.73 TSHR (0.54) ALDH1A1TSHRMEN1KMT2APIN1
Biphenyl SCHEMBL28053100 0.73 PIN1 (0.50) ALDH1A1TSHRMEN1KMT2APIN1
Biphenyl SCHEMBL27438624 0.72 ACP3 (0.54) ALDH1A1TSHRMEN1KMT2AACP3
SCHEMBL28434406 0.72 GAA (0.52) MEN1KMT2APIN1MMP8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748543-B2 Polylactic acid film TEIJIN LIMITED (JP) 2014-06-10 US disclosed
US-20110224342-A1 POLYLACTIC ACID FILM TEIJIN LIMITED (JP) 2011-09-15 US disclosed
EP-2330148-A1 POLYLACTIC ACID FILM Teijin Limited (JP) 2011-06-08 EP disclosed