Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30826553 | 0.78 | PDE4B (0.44) | MAPTCHRM1PDE4AADRA1APDE1A | |
| SCHEMBL21241613 | 0.78 | PDE4B (0.44) | MAPTCHRM1PDE4AADRA1APDE1A | |
| SCHEMBL28602490 | 0.78 | PDE4B (0.41) | MAPTCHRM1PDE4AADRA1APDE1A | |
| SCHEMBL2476070 | 0.78 | NPC1 (0.47) | MAPTNPC1KDM4EMEN1MAPK1 | |
| SCHEMBL860782 | 0.76 | MERTK (0.68) | MERTKMAPTVCAM1PDE7APKM | |
| SCHEMBL10656431 | 0.75 | ALDH1A1 (0.47) | MAPTPKMNPC1KDM4EMEN1 | |
| SCHEMBL20982786 | 0.75 | MERTK (0.56) | MERTKMAPTVCAM1PDE7APKM | |
| SCHEMBL10657383 | 0.73 | PRMT5 (0.37) | MAPTPKMNPC1KDM4EMEN1 | |
| SCHEMBL29406469 | 0.72 | ALDH1A1 (0.40) | MAPTVCAM1NPC1KDM4ELMNA | |
| SCHEMBL11289001 | 0.71 | MEN1 (0.45) | MAPTKDM4EMEN1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018150327-A1 | CRISABOROLE PRODUCTION PROCESS | WAVELENGTH ENTERPRISES LTD (IL) | 2018-08-23 | — | — | WO | claimed |
| WO-2018150327-A1 | CRISABOROLE PRODUCTION PROCESS | WAVELENGTH ENTERPRISES LTD (IL) | 2018-08-23 | — | — | WO | disclosed |