Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29403691 | 0.89 | ALDH1A1 (0.40) | ALDH1A1HPGDHTTKIF11L3MBTL1 | |
| SCHEMBL11168137 | 0.75 | TSHR (0.53) | ALDH1A1HPGDHTTL3MBTL1GAA | |
| SCHEMBL29404173 | 0.74 | HTT (0.40) | ALDH1A1HTTL3MBTL1MAPTRAB9A | |
| SCHEMBL10658982 | 0.74 | BACE1 (0.41) | ALDH1A1HTTL3MBTL1MAPTRAB9A | |
| SCHEMBL20328777 | 0.74 | TSHR (0.53) | ALDH1A1HTTMAPTPOLBKMT2A | |
| SCHEMBL17395909 | 0.74 | TDP1 (0.51) | ALDH1A1HTTL3MBTL1MAPTPOLB | |
| SCHEMBL44775 | 0.74 | MAPK1 (0.51) | ALDH1A1HTTL3MBTL1MAPTLMNA | |
| SCHEMBL29406601 | 0.74 | HTT (0.35) | HTTMAPTCUL4A | |
| SCHEMBL29406166 | 0.74 | HTT (0.35) | ALDH1A1HTTMAPTLMNAPOLB | |
| SCHEMBL20339048 | 0.72 | TDP1 (0.53) | ALDH1A1HPGDL3MBTL1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053567-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA CROP PROTECTION AG (CH) | 2022-03-17 | — | — | WO | disclosed |