Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440458 | 0.72 | KDM4E (0.50) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL444231 | 0.71 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL20961019 | 0.65 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL19222727 | 0.65 | KDM4E (0.39) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL439205 | 0.62 | CHRNB2 (0.47) | ALDH1A1 | |
| SCHEMBL25524450 | 0.61 | KDM4E (0.45) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL14922437 | 0.59 | KDM4E (0.34) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL2026380 | 0.59 | — | — | |
| SCHEMBL4898541 | 0.58 | CYP19A1 (0.41) | CA1CA2CA4 | |
| SCHEMBL12464963 | 0.58 | CYP19A1 (0.41) | CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2345639-A1 | Cyclic hydroxylamine derivatives, their preparation and use as antioxidants | ABIOGEN PHARMA S.p.A. (IT) | 2011-07-20 | — | — | EP | disclosed |
| EP-2345639-A1 | Cyclic hydroxylamine derivatives, their preparation and use as antioxidants | ABIOGEN PHARMA S.p.A. (IT) | 2011-07-20 | — | — | EP | disclosed |
| WO-2011076930-A1 | CYCLIC HYDROXYLAMINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTIOXIDANTS | ABIOGEN PHARMA S.P.A. (IT) | 2011-06-30 | — | — | WO | disclosed |
| WO-2011076930-A1 | CYCLIC HYDROXYLAMINE DERIVATIVES, THEIR PREPARATION AND USE AS ANTIOXIDANTS | ABIOGEN PHARMA S.P.A. (IT) | 2011-06-30 | — | — | WO | disclosed |