Biphenyl

Biphenyl

SCHEMBL2047773

O=[PH](O)OCC(CO)(CO)CO[PH](=O)O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.34
HIF1A Q16665 1/20 0.34
HTT P42858 2/20 0.34
RAB9A P51151 1/20 0.34
S1PR1 P21453 2/20 0.34
S1PR3 Q99500 1/20 0.34
MMP2 P08253 1/20 0.33
MMP7 P09237 1/20 0.33
MMP14 P50281 1/20 0.33
ABCC4 O15439 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
TSHR P16473 1/20 0.32
PTGS1 P23219 1/20 0.32
ALDH1A1 P00352 2/20 0.32
GGPS1 O95749 1/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
CYP2C9 P11712 1/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19744359 0.86 TDP1 (0.39) MAPK1S1PR1S1PR3LMNAALDH1A1
SCHEMBL864630 0.82 ALDH1A1 (0.32) MAPK1HIF1AALDH1A1SMN1; SMN2
Biphenyl SCHEMBL10634583 0.79 ALDH1A1 (0.39) HIF1AHTTRAB9AABCC4LMNA
SCHEMBL10349981 0.78 ALDH1A1 (0.32) MAPK1HIF1AALDH1A1SMN1; SMN2
Biphenyl SCHEMBL18394369 0.75 SMN1; SMN2 (0.44) HTTRAB9AABCC4LMNAGAA
SCHEMBL269493 0.74 ALDH1A1 (0.33) MAPK1HIF1AALDH1A1KDM4EPOLB
Biphenyl SCHEMBL3688776 0.73 ALDH1A1 (0.53) MAPK1HTTRAB9AABCC4LMNA
SCHEMBL11020720 0.73 CYP1A2 (0.39) MAPK1HIF1ATSHRALDH1A1CYP2C9
Ethyl Chloride SCHEMBL11767125 0.69
Biphenyl SCHEMBL9009481 0.69 ALDH1A1 (0.47) HTTRAB9AABCC4LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4683971-A1 FLAME RETARDANTS FOR ELASTIC POLYAMIDE COMPOSITIONS Ascend Performance Materials Operations LLC (US) 2026-01-28 EP disclosed
WO-2024197178-A1 FLAME RETARDANTS FOR ELASTIC POLYAMIDE COMPOSITIONS ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2024-09-26 WO disclosed
CN-109477000-B Flame retardant additives for polymers 聚丙烯聚合物股份公司 2021-04-06 CN disclosed
US-10947379-B2 Flame retardant additive for polymers PP POLYMER AB (SE) 2021-03-16 US disclosed
US-10919923-B2 Organic phosphorus-based compound, and flame retardant and flame-retardant product comprising the same TEIJIN LIMITED (JP) 2021-02-16 US disclosed
EP-3514161-B1 ORGANOPHOSPHORUS COMPOUND, FLAME RETARDANT, AND FLAME-RETARDANT PRODUCT INCLUDING SAME TEIJIN LTD (JP) 2020-05-13 EP disclosed
EP-3514161-A1 ORGANOPHOSPHORUS COMPOUND, FLAME RETARDANT, AND FLAME-RETARDANT PRODUCT INCLUDING SAME Teijin Limited (JP) 2019-07-24 EP disclosed
US-20190218237-A1 ORGANIC PHOSPHORUS-BASED COMPOUND, AND FLAME RETARDANT AND FLAME-RETARDANT PRODUCT COMPRISING THE SAME TEIJIN LIMITED (JP) 2019-07-18 US disclosed
US-20190127568-A1 FLAME RETARDANT ADDITIVE FOR POLYMERS PP POLYMER AB (SE) 2019-05-02 US disclosed
EP-3472263-A1 FLAME RETARDANT ADDITIVE FOR POLYMERS PP Polymer AB (SE) 2019-04-24 EP disclosed
WO-2017222448-A1 FLAME RETARDANT ADDITIVE FOR POLYMERS PP POLYMER AB (SE) 2017-12-28 WO disclosed
US-8222330-B2 Polycarbonate resin composition having good flame retardancy CHEIL INDUSTRIES INC. (KR) 2012-07-17 US disclosed
US-20110160367-A1 Polycarbonate Resin Composition Having Good Flame Retardancy CHEIL INDUSTRIES INC. (KR) 2011-06-30 US disclosed
US-4520152-A PENTAERYTHRITOL PHOSPHONATE COMPOUNDS GENERAL ELECTRIC COMPANY (US) 1985-05-28 US disclosed
US-4390477-A FIREPROOFING GENERAL ELECTRIC COMPANY (US) 1983-06-28 US disclosed
US-4178281-A Flame-retardant polycarbonate compositions BORG-WARNER CORPORATION (US) 1979-12-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919923-B2 Organic phosphorus-based compound, and flame retardant and flame-retardant product comprising the same PF4, TPD52L2, AFF4 MAPK1 2234/4885HIF1A 3664/4885HTT 4265/4885
US-20190218237-A1 ORGANIC PHOSPHORUS-BASED COMPOUND, AND FLAME RETARDANT AND FLAME-RETARDANT PRODUCT COMPRISING THE SAME PF4, TPD52L2, AFF4 MAPK1 2234/4885HIF1A 3664/4885HTT 4265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.