Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.67 |
| ▸ | NR4A1 | P22736 | 7/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.65 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.65 |
| ▸ | CCR6 | P51684 | 1/20 | 0.65 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.65 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.65 |
| ▸ | PRDX1 | Q06830 | 4/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL720070 | 1.00 | TERT (0.67) | TERTNR4A1PTPN1CASP1ABHD6 | |
| SCHEMBL17328976 | 0.90 | HSP90AA1 (0.73) | TERTNR4A1PTPN1CASP1ABHD6 | |
| SCHEMBL17328954 | 0.89 | NR4A1 (0.70) | TERTNR4A1PTPN1CASP1ABHD6 | |
| SCHEMBL20022 | 0.89 | NR4A1 (0.70) | TERTNR4A1PTPN1CASP1ABHD6 | |
| SCHEMBL18781875 | 0.88 | NR4A1 (0.73) | TERTNR4A1PTPN1CASP1ABHD6 | |
| SCHEMBL20433 | 0.87 | TERT (0.72) | TERTNR4A1PTPN1CASP1ABHD6 | |
| SCHEMBL18781870 | 0.85 | NR4A1 (0.72) | TERTNR4A1PTPN1CASP1ABHD6 | |
| SCHEMBL22822455 | 0.85 | PRDX1 (0.79) | TERTNR4A1PTPN1CASP1ABHD6 | |
| SCHEMBL17328937 | 0.84 | TERT (0.71) | TERTNR4A1PTPN1CASP1ABHD6 | |
| SCHEMBL17328914 | 0.84 | TERT (0.71) | TERTNR4A1PTPN1CASP1ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609108-B1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | SUZHOU NEUPHARMA CO LTD (CN) | 2015-12-16 | — | — | EP | claimed |
| EP-2609108-B1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | SUZHOU NEUPHARMA CO LTD (CN) | 2015-12-16 | — | — | EP | disclosed |
| US-20120052019-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | NEUPHARMA, INC. | 2012-03-01 | — | — | US | disclosed |
| US-20120052019-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | NEUPHARMA, INC. | 2012-03-01 | — | — | US | disclosed |
| US-20120052019-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | NEUPHARMA, INC. | 2012-03-01 | — | — | US | disclosed |
| WO-2012024893-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | SUZHOU NEUPHARMA CO., LTD. (CN) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052019-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | LTB4R2, PTGER4, PMP22 | TERT 282/4885NR4A1 352/4885PTPN1 2274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.