SCHEMBL2047906

SCHEMBL2047906

C1CCC(OC2=NCCO2)CC1.C=CCOC1=NCCO1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
ADRA1A P35348 1/20 0.33
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL961432 0.83 ADRA2A (0.43) ADRA2AADRA2BADRA2CADRA1A
SCHEMBL959643 0.83
SCHEMBL959037 0.82 ADRA2A (0.40) ADRA2AADRA2BADRA2CADRA1A
SCHEMBL1842945 0.75 NOS3 (0.38) ADRA2AADRA2BADRA2CADRA1A
SCHEMBL1842229 0.73 NOS3 (0.39) ADRA2AADRA2BADRA2CADRA1A
SCHEMBL960792 0.64
SCHEMBL4856712 0.64
SCHEMBL4860672 0.62 HDAC3 (0.33)
SCHEMBL3942984 0.60 NPC1 (0.40) NPC1MAPTRAB9A
SCHEMBL49322 0.60 NPC1 (0.40) NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140066555-A1 POLYLACTIC ACID COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2014-03-06 US disclosed
EP-2698252-A1 ORIENTED LAMINATED FILM Teijin Limited (JP) 2014-02-19 EP disclosed
US-8647738-B2 Film TEIJIN LIMITED (JP) 2014-02-11 US disclosed
US-20140030499-A1 ORIENTED LAMINATED FILM TEIJIN LIMITED (JP) 2014-01-30 US disclosed
US-20110263762-A1 POLYLACTIC ACID COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2011-10-27 US disclosed
EP-2351792-A1 POLYLACTIC ACID COMPOSITIONS AND MOLDED ARTICLES THEREOF Teijin Chemicals, Ltd. (JP) 2011-08-03 EP disclosed
US-20110160364-A1 RESIN COMPOSITION, MANUFACTURING METHOD THEREOF, AND MOLDED ARTICLE TEIJIN LIMITED (JP) 2011-06-30 US disclosed
US-20100324220-A1 RESIN COMPOSITION AND MOLDED ARTICLE TEIJIN LIMITED (JP) 2010-12-23 US disclosed
EP-2256165-A1 RESIN COMPOSITION AND MOLDED ARTICLE Teijin Limited (JP) 2010-12-01 EP disclosed
US-20100182694-A1 FILM TEIJIN LIMITED (JP) 2010-07-22 US disclosed
EP-2189493-A1 FILM Teijin Limited (JP) 2010-05-26 EP disclosed
EP-2053091-A1 RESIN COMPOSITION, METHOD FOR PRODUCING THE SAME AND MOLDED ARTICLE TEIJIN LIMITED (JP) 2009-04-29 EP disclosed