Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16989311 | 1.00 | KMT2A (0.52) | KMT2AALDH1A1GAAMEN1CASR | |
| SCHEMBL27045518 | 1.00 | KMT2A (0.52) | KMT2AALDH1A1GAAMEN1CASR | |
| SCHEMBL16997632 | 0.94 | ALDH1A1 (0.55) | KMT2AALDH1A1GAAMEN1CASR | |
| SCHEMBL16997627 | 0.91 | KMT2A (0.43) | KMT2AALDH1A1GAAMEN1CASR | |
| SCHEMBL20901310 | 0.91 | KMT2A (0.43) | KMT2AALDH1A1GAAMEN1CASR | |
| SCHEMBL16989098 | 0.89 | ALDH1A1 (0.47) | KMT2AALDH1A1GAAMEN1CMA1 | |
| SCHEMBL16997630 | 0.88 | FKBP1A (0.46) | ALDH1A1KDM4ETP53MAPT | |
| SCHEMBL24092107 | 0.87 | KMT2A (0.46) | KMT2AALDH1A1GAAMEN1CASR | |
| SCHEMBL16997629 | 0.85 | ALDH1A1 (0.51) | KMT2AALDH1A1GAAMEN1 | |
| SCHEMBL16997844 | 0.84 | KMT2A (0.41) | KMT2AALDH1A1GAAMEN1CASR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4309653-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | Exithera Pharmaceuticals Inc. (US) | 2024-01-24 | — | — | EP | disclosed |
| US-10259785-B2 | Therapeutic compounds and compositions | EXITHERA PHARMACEUTICALS, INC. (US) | 2019-04-16 | — | — | US | disclosed |
| US-20180244614-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | EXITHERA PHARMACEUTICALS, INC. | 2018-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10259785-B2 | Therapeutic compounds and compositions | KLK5, KLKB1, KLK2 | KMT2A 973/4885ALDH1A1 4490/4885GAA 1486/4885 |
| US-20180244614-A1 | THERAPEUTIC COMPOUNDS AND COMPOSITIONS | KLK5, KLKB1, KLK2 | KMT2A 973/4885ALDH1A1 4490/4885GAA 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.