Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Dipyridyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.93 |
| ▸ | LMNA | P02545 | 3/20 | 0.93 |
| ▸ | CCR1 | P32246 | 3/20 | 0.93 |
| ▸ | CCR5 | P51681 | 3/20 | 0.93 |
| ▸ | CCR8 | P51685 | 3/20 | 0.93 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.93 |
| ▸ | POLB | P06746 | 1/20 | 0.93 |
| ▸ | METAP1 | P53582 | 1/20 | 0.93 |
| ▸ | BLM | P54132 | 1/20 | 0.93 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.93 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.93 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.93 |
| ▸ | NPC1 | O15118 | 6/20 | 0.74 |
| ▸ | TP53 | P04637 | 4/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dipyridyl SCHEMBL30063914 | 1.00 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29351528 | 0.97 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL5922 | 0.97 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL29907716 | 0.97 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL3711450 | 0.97 | KDM4E (1.00) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL1927728 | 0.93 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL2374297 | 0.93 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL6403001 | 0.93 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL9821490 | 0.93 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| Dipyridyl SCHEMBL6408082 | 0.93 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003207-A | Preparation method of difluoro sulfimide and alkali metal salt thereof | 湖南福邦新材料有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-117003207-A | Preparation method of difluoro sulfimide and alkali metal salt thereof | 湖南福邦新材料有限公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-105297067-B | A kind of multicell diaphragm electrolysis method and apparatus by carbon dioxide electroreduction for carbon monoxide | 昆明理工大学 | 2018-02-09 | — | — | CN | disclosed |
| EP-2507306-B1 | USE OF METAL COMPLEXES AS OXYGEN ABSORBER/SCAVENGER ELEMENTS FOR PACKAGING APPLICATIONS | BASF SE (DE) | 2017-01-18 | — | — | EP | disclosed |
| CN-205329170-U | Multi -chambered diaphragm electrolysis device that is carbon dioxide electroreduction carbon monoxide | 昆明理工大学 | 2016-06-22 | — | — | CN | disclosed |
| CN-105297067-A | Multi-room diaphragm electrolysis method and device for electroreduction of carbon dioxide into carbon monoxide | UNIV KUNMING SCIENCE & TECHNOLOGY | 2016-02-03 | — | — | CN | disclosed |
| US-20120263974-A1 | USE OF METAL COMPLEXES AS OXYGEN ABSORBER/SCAVENGER ELEMENTS FOR PACKAGING APPLICATIONS | BASF SE (DE) | 2012-10-18 | — | — | US | disclosed |
| EP-2507306-A1 | USE OF METAL COMPLEXES AS OXYGEN ABSORBER/SCAVENGER ELEMENTS FOR PACKAGING APPLICATIONS | BASF SE (DE) | 2012-10-10 | — | — | EP | disclosed |
| WO-2011067198-A1 | USE OF METAL COMPLEXES AS OXYGEN ABSORBER/SCAVENGER ELEMENTS FOR PACKAGING APPLICATIONS | BASF SE (DE) | 2011-06-09 | — | — | WO | disclosed |