SCHEMBL2048074

SCHEMBL2048074

C=C(CCCC=O)C(=O)O.C=C(CCCC=O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.41
ALOX15 P16050 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TBXAS1 P24557 2/20 0.36
TSHR P16473 2/20 0.35
TET2 Q6N021 4/20 0.33
TET3 O43151 1/20 0.33
TET1 Q8NFU7 1/20 0.33
MAPT P10636 2/20 0.32
GRIK1 P39086 1/20 0.32
GRIK2 Q13002 1/20 0.32
GRM1 Q13255 1/20 0.32
GRM2 Q14416 1/20 0.32
ABCC4 O15439 1/20 0.32
LMNA P02545 1/20 0.30
ALKBH5 Q6P6C2 1/20 0.30
SUCNR1 Q9BXA5 1/20 0.30
EGLN1 Q9GZT9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1824152 1.00 HIF1A (0.41) HIF1AALOX15HSD17B10TBXAS1TSHR
SCHEMBL2046603 0.93 MAPT (0.40) HIF1AALOX15HSD17B10TBXAS1TSHR
SCHEMBL1832017 0.93 MAPT (0.40) HIF1AALOX15HSD17B10TBXAS1TSHR
SCHEMBL10337658 0.91 MAPT (0.43) HIF1AALOX15HSD17B10TBXAS1TSHR
SCHEMBL16661276 0.91 MAPT (0.43) HIF1AALOX15HSD17B10TBXAS1TSHR
SCHEMBL4953960 0.91 MAPT (0.43) HIF1AALOX15HSD17B10TBXAS1TSHR
SCHEMBL1821741 0.85
SCHEMBL2119324 0.81 MAPT (0.52) ALOX15HSD17B10TBXAS1TSHRTET2
SCHEMBL720674 0.79 ALOX15 (0.35) ALOX15HSD17B10TBXAS1TET2TET3
SCHEMBL10792586 0.79 HIF1A (0.39) HIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110144267-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD EVONIK ROEHM GMBH (DE) 2011-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144267-A1 FUNCTIONALIZED (METH)ACRYLATE MONOMER, POLYMER, COATING AGENT, AND PRODUCTION AND CROSS-LINKING METHOD DNMT1, TET1, MGMT HIF1A 161/4885ALOX15 3498/4885HSD17B10 1425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.