SCHEMBL720674

SCHEMBL720674

C=C(CCCC=S)C(=O)O

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TBXAS1 P24557 2/20 0.35
TET2 Q6N021 4/20 0.32
TET3 O43151 1/20 0.32
TET1 Q8NFU7 1/20 0.32
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
GRM1 Q13255 1/20 0.31
GRM2 Q14416 1/20 0.31
ABCC4 O15439 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL723346 0.93 MAPT (0.39) ALOX15HSD17B10TBXAS1TET2ABCC4
SCHEMBL50377 0.86
SCHEMBL1824152 0.79 HIF1A (0.41) ALOX15HSD17B10TBXAS1TET2TET3
SCHEMBL2119324 0.79 MAPT (0.52) ALOX15HSD17B10TBXAS1TET2TET3
SCHEMBL2048074 0.79 HIF1A (0.41) ALOX15HSD17B10TBXAS1TET2TET3
SCHEMBL7989948 0.77 SLC22A6 (0.44) ALOX15HSD17B10TBXAS1TET2TET3
SCHEMBL2025802 0.77 TBXAS1 (0.47) ALOX15HSD17B10TBXAS1TET2TET3
SCHEMBL6067655 0.75
SCHEMBL11122641 0.75 TBXAS1 (0.50) ALOX15HSD17B10TBXAS1TET2TET3
SCHEMBL3125930 0.75 TBXAS1 (0.50) ALOX15HSD17B10TBXAS1TET2TET3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8727135-B2 Composite filtration membranes and methods of preparation thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2014-05-20 US disclosed
US-20120048798-A1 COMPOSITE FILTRATION MEMBRANES AND METHODS OF PREPARATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2012-03-01 US disclosed
US-7282322-B2 Long-term high temperature and humidity stable holographic optical data storage media compositions with exceptional high dynamic range ACADIA WOODS PARTNERS, LLC 2007-10-16 US disclosed
EP-1508144-B1 HOLOGRAPHIC DATA STORAGE MEDIA COMPRISING AN ALUMINUM SALT COMPOUND AND AN ASYMMETRIC ACRYLATE COMPOUND INPHASE TECH INC (US) 2006-06-21 EP disclosed
US-20050259303-A1 Long-term high temperature and humidity stable holographic optical data storage media compositions with exceptional high dynamic range ACADIA WOODS PARTNERS, LLC 2005-11-24 US disclosed
CN-1666294-A Holographic data storage media comprising an aluminum salt compound and an asymetric acrylate compound INPHASE TECH INC (US) 2005-09-07 CN disclosed
EP-1508144-A1 HOLOGRAPHIC DATA STORAGE MEDIA COMPRISING AN ALUMINUM SALT COMPOUND AND AN ASYMMETRIC ACRYLATE COMPOUND InPhase Technologies, Inc. (US) 2005-02-23 EP disclosed
WO-2003102959-A1 HOLOGRAPHIC DATA STORAGE MEDIA COMPRISING AN ALUMINUM SALT COMPOUND AND AN ASYMETRIC ACRYLATE COMPOUND INPHASE TECHNOLOGIES, INC. (US) 2003-12-11 WO disclosed
US-5728779-A BINDER FOR THERMOSETTING POWDER PAINTS DSM N.V. (NL) 1998-03-17 US disclosed