Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 6/20 | 0.58 |
| ▸ | RORC | P51449 | 4/20 | 0.58 |
| ▸ | RORA | P35398 | 3/20 | 0.58 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.58 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | OSBP | P22059 | 4/20 | 0.53 |
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | CDC25A | P30304 | 2/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20481953 | 1.00 | GPR183 (0.58) | GPR183RORCRORANPC1L1PLA2G1B | |
| SCHEMBL22959587 | 1.00 | GPR183 (0.58) | GPR183RORCRORANPC1L1PLA2G1B | |
| SCHEMBL18584449 | 1.00 | GPR183 (0.58) | GPR183RORCRORANPC1L1PLA2G1B | |
| SCHEMBL18584451 | 1.00 | GPR183 (0.58) | GPR183RORCRORANPC1L1PLA2G1B | |
| SCHEMBL18714203 | 0.80 | RORC (0.62) | GPR183RORCRORANPC1L1PLA2G1B | |
| SCHEMBL18714205 | 0.80 | RORC (0.62) | GPR183RORCRORANPC1L1PLA2G1B | |
| SCHEMBL13966714 | 0.80 | RORC (0.62) | GPR183RORCRORANPC1L1PLA2G1B | |
| SCHEMBL25774172 | 0.78 | RORC (0.59) | GPR183RORCRORANPC1L1PLA2G1B | |
| SCHEMBL6119630 | 0.78 | RORC (0.59) | GPR183RORCRORANPC1L1PLA2G1B | |
| SCHEMBL27322122 | 0.77 | RORC (0.56) | GPR183RORCRORANPC1L1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4706644-A1 | RECONSTITUTED HIGH-DENSITY LIPOPROTEIN NANOPARTICLES COMPRISING CHOLESTEROL | Mepsgen Co., Ltd. (KR) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228596-A1 | RECONSTITUTED HIGH-DENSITY LIPOPROTEIN NANOPARTICLES COMPRISING CHOLESTEROL | (주) 멥스젠 | 2024-11-07 | — | — | WO | claimed |
| EP-4706644-A1 | RECONSTITUTED HIGH-DENSITY LIPOPROTEIN NANOPARTICLES COMPRISING CHOLESTEROL | Mepsgen Co., Ltd. (KR) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228596-A1 | RECONSTITUTED HIGH-DENSITY LIPOPROTEIN NANOPARTICLES COMPRISING CHOLESTEROL | (주) 멥스젠 | 2024-11-07 | — | — | WO | disclosed |
| US-20210041466-A1 | DIAGNOSTIC METHODS AND KITS | CHOLESTENIX LTD (GB) | 2021-02-11 | — | — | US | disclosed |
| EP-3345004-B1 | DIAGNOSTIC METHODS AND KITS | CHOLESTENIX LTD (GB) | 2020-07-22 | — | — | EP | disclosed |
| US-20180246128-A1 | DIAGNOSTIC METHODS AND KITS | SWANSEA UNIVERSITY (GB) | 2018-08-30 | — | — | US | disclosed |