Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20482573 | 0.88 | ITGB1 (0.46) | ITGB1ITGA4KMT2AMEN1ACACB | |
| SCHEMBL8586015 | 0.78 | ALDH1A1 (0.52) | ITGB1ITGA4KMT2AMEN1POLB | |
| SCHEMBL20482975 | 0.77 | TSHR (0.40) | KMT2AMEN1ALDH1A1TSHRMCOLN3 | |
| SCHEMBL20482446 | 0.76 | TSHR (0.38) | ITGB1ITGA4KMT2AACACBALDH1A1 | |
| SCHEMBL28840825 | 0.75 | CYP4F2 (0.42) | KMT2APOLBALDH1A1P2RX7 | |
| SCHEMBL12353911 | 0.75 | CYP4F2 (0.44) | KMT2AMEN1POLBALDH1A1LMNA | |
| SCHEMBL4907162 | 0.75 | TACR1 (0.47) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL5750629 | 0.75 | POLB (0.46) | KMT2APOLBALDH1A1LMNAP2RX7 | |
| SCHEMBL20482542 | 0.73 | ITGB1 (0.41) | ITGB1ITGA4KMT2AMEN1ALDH1A1 | |
| SCHEMBL30683842 | 0.73 | TACR1 (0.48) | KMT2AMEN1ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018154466-A1 | DIHYDROQUINOLIZINONES AS ANTIVIRALS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-08-30 | — | — | WO | disclosed |