Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.46 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | SELP | P16109 | 3/20 | 0.38 |
| ▸ | SELL | P14151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20482379 | 0.88 | ITGB1 (0.46) | ITGB1ITGA4TSHRMCOLN3KMT2A | |
| SCHEMBL20482542 | 0.84 | ITGB1 (0.41) | ITGB1ITGA4KMT2AALDH1A1MEN1 | |
| SCHEMBL20482392 | 0.83 | ALDH1A1 (0.51) | ITGB1ITGA4TSHRKMT2AALDH1A1 | |
| SCHEMBL20482686 | 0.82 | ITGB1 (0.39) | ITGB1ITGA4KMT2AALDH1A1MEN1 | |
| SCHEMBL2961711 | 0.81 | KMT2A (0.43) | ITGB1ITGA4TSHRKMT2AALDH1A1 | |
| SCHEMBL27585681 | 0.79 | PDE4A (0.52) | — | |
| SCHEMBL20482458 | 0.79 | HPGD (0.47) | KMT2AALDH1A1GAANFKB1MEN1 | |
| SCHEMBL20482975 | 0.78 | TSHR (0.40) | TSHRMCOLN3KMT2AALDH1A1MEN1 | |
| SCHEMBL20482676 | 0.78 | SMPD1 (0.52) | TSHRKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL6627416 | 0.77 | ITGB1 (0.47) | ITGB1ITGA4TSHRKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018154466-A1 | DIHYDROQUINOLIZINONES AS ANTIVIRALS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-08-30 | — | — | WO | disclosed |