⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476123 | 0.78 | — | — | |
| SCHEMBL253162 | 0.77 | — | — | |
| SCHEMBL175854 | 0.77 | — | — | |
| SCHEMBL756566 | 0.74 | — | — | |
| SCHEMBL6310315 | 0.74 | — | — | |
| SCHEMBL170733 | 0.74 | — | — | |
| SCHEMBL14889353 | 0.74 | — | — | |
| SCHEMBL6427762 | 0.72 | — | — | |
| SCHEMBL756567 | 0.72 | — | — | |
| SCHEMBL7695919 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921762-B2 | Substituted indolizine-like compounds and methods of use | AMGEN INC. (US) | 2005-07-26 | — | — | US | claimed |
| EP-3092237-A1 | HETEROARYL SULTAM DERIVATIVES AS RORc MODULATORS | F. Hoffmann-La Roche AG (CH) | 2016-11-16 | — | — | EP | disclosed |
| US-20160311817-A1 | HETEROARYL SULTAM DERIVATIVES AS RORc MODULATORS | GENENTECH, INC. (US) | 2016-10-27 | — | — | US | disclosed |
| WO-2015104353-A1 | HETEROARYL SULTAM DERIVATIVES AS RORc MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-07-16 | — | — | WO | disclosed |
| JP-2011121884-A | METHOD FOR PRODUCING FLUORINE-CONTAINING ALKYLSULFONAMIDE ALCOHOL AND DERIVATIVE THEREOF | CENTRAL GLASS CO LTD | 2011-06-23 | — | — | JP | disclosed |
| EP-0112725-B1 | CHLOROSULPHONATED POLYSULPHONES AND POLYSULPHONE SULPHONAMIDES | ALBANY INTERNATIONAL CORP. (US) | 1988-04-13 | — | — | EP | disclosed |
| EP-0112725-A1 | Chlorosulphonated polysulphones and polysulphone sulphonamides | ALBANY INTERNATIONAL CORP. (US) | 1984-07-04 | — | — | EP | disclosed |
| US-4414368-A | Chlorosulfonated polysulfones and derivatives thereof | ALBANY INTERNATIONAL CORP. (US) | 1983-11-08 | — | — | US | disclosed |
| US-4101468-A | Process for cold-hardening polyurethane foams using sulfonamide emulsifiers | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-18 | — | — | US | disclosed |
| US-3979454-A | Process for the production of alkyl sulphonic acid hydroxy alkyl amides | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-07 | — | — | US | disclosed |