⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175854 | 0.79 | — | — | |
| SCHEMBL253162 | 0.79 | — | — | |
| SCHEMBL756566 | 0.77 | — | — | |
| SCHEMBL1517768 | 0.74 | — | — | |
| SCHEMBL2981480 | 0.74 | — | — | |
| SCHEMBL7695919 | 0.74 | — | — | |
| SCHEMBL6427762 | 0.74 | — | — | |
| SCHEMBL6887926 | 0.74 | — | — | |
| SCHEMBL2048296 | 0.74 | — | — | |
| SCHEMBL756567 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921762-B2 | Substituted indolizine-like compounds and methods of use | AMGEN INC. (US) | 2005-07-26 | — | — | US | claimed |