Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | CDC25A | P30304 | 1/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | CETP | P11597 | 3/20 | 0.50 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | PTAFR | P25105 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14000864 | 1.00 | LMNA (0.58) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL21580898 | 1.00 | LMNA (0.58) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL19458808 | 1.00 | LMNA (0.58) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL27699112 | 1.00 | LMNA (0.58) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL20482670 | 1.00 | LMNA (0.58) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL12235520 | 1.00 | LMNA (0.58) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL27542770 | 1.00 | LMNA (0.58) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL28786169 | 0.98 | LMNA (0.56) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL29267508 | 0.91 | LPAR3 (0.53) | LMNAESR1ADORA3CDC25AAGTR1 | |
| SCHEMBL27747029 | 0.91 | LPAR3 (0.53) | LMNAESR1ADORA3CDC25AAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3586142-B1 | DETECTION OF MEMBRANE PROTEINS | UNIV OXFORD INNOVATION LTD (GB) | 2024-12-25 | — | — | EP | disclosed |
| US-10955421-B2 | Detection of membrane proteins | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2021-03-23 | — | — | US | disclosed |
| US-20200240997-A1 | DETECTION OF MEMBRANE PROTEINS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2020-07-30 | — | — | US | disclosed |
| WO-2018154318-A1 | DETECTION OF MEMBRANE PROTEINS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2018-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200240997-A1 | DETECTION OF MEMBRANE PROTEINS | CETP, VAPA, PCTP | LMNA 1166/4885ESR1 3145/4885ADORA3 4602/4885 |
| US-10955421-B2 | Detection of membrane proteins | CETP, VAPA, PCTP | LMNA 1166/4885ESR1 3145/4885ADORA3 4602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.