Iodide

Iodide

SCHEMBL2048342

[Al+2]Cc1ccccc1.[I-].[I-]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.50
TSHR P16473 4/20 0.45
ALDH1A1 P00352 3/20 0.45
IDO1 P14902 3/20 0.45
LOXL2 Q9Y4K0 2/20 0.45
TP53 P04637 1/20 0.45
TRPA1 O75762 1/20 0.45
MAOB P27338 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
ALOX12 P18054 1/20 0.43
CASP1 P29466 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TDP1 Q9NUW8 2/20 0.41
CYP2A6 P11509 1/20 0.41
HTR2A P28223 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
THRB P10828 1/20 0.39
EPHX2 P34913 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL726522 0.93 CALM1 (0.50) CALM1TSHRALDH1A1IDO1LOXL2
Bromide SCHEMBL2050558 0.93 CALM1 (0.50) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL5897377 0.93
Hydrochloric Acid SCHEMBL11763102 0.83 IDO1 (0.43) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL29691624 0.83 TP53 (0.50) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL150773 0.69
Fluoride Ion SCHEMBL12481853 0.69 ALDH1A1 (0.52) CALM1TSHRALDH1A1IDO1LOXL2
Hydrochloric Acid SCHEMBL150415 0.69 ALDH1A1 (0.52) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL62125 0.67 ALDH1A1 (0.69) CALM1ALDH1A1LOXL2MAOBHPGD
Diphenylmethane SCHEMBL1303 0.67 CALM1 (1.00) CALM1TSHRALDH1A1IDO1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3995095-A Modification of polymers by treatment with olefins PHILLIPS PETROLEUM COMPANY (US) 1976-11-30 US claimed
US-20200179914-A1 METHOD FOR PRODUCING CATALYST POLYPLASTICS CO., LTD. (JP) 2020-06-11 US disclosed
EP-2057205-B1 PRODUCTION OF META-BLOCK COPOLYMERS BY POLYMER SEGMENT INTERCHANGE DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-08 EP disclosed
EP-2061827-B1 PRODUCTION OF BLOCKCOPOLYMERS BY AMORPHOUS POLYMER SEGMENT INTERCHANGE VIA METATHESIS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-03-02 EP disclosed
US-8557921-B2 Production of meta-block copolymers by polymer segment interchange DOW GLOBAL TECHNOLOGIES LLC 2013-10-15 US disclosed
US-8530579-B2 Production of metathesis products by high melting polymer segment interchange DOW GLOBAL TECHNOLOGIES LLC 2013-09-10 US disclosed
EP-2061826-B1 PRODUCTION OF RANDOM BLOCKCOPOLYMERS VIA HIGH MELTING POLYMER SEGMENT METATHESIS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-08-01 EP disclosed
US-8048961-B2 Production of metathesis products by amorphous polymer segment interchange DOW GLOBAL TECHNOLOGIES LLC (US) 2011-11-01 US disclosed
CN-101516916-B Preparation of telechelic compounds by metathesis depolymerization DOW GLOBAL TECHNOLOGIES INC 2011-09-28 CN disclosed
US-7956132-B2 Production of telechelic compounds by metathesis depolymerization DOW GLOBAL TECHNOLOGIES LLC (US) 2011-06-07 US disclosed
EP-0235742-B1 PREPARATION OF 9-ALKENYL ESTER COMPOUNDS PHILLIPS PETROLEUM COMPANY (US) 1991-05-15 EP disclosed
US-4232180-A PENTENE AND CYCLOPENTENE, CATALYST OF ALKYLALUMINUM CHLORIDE, TUNGSTEN HALIDE AND AN ALCOHOL THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-11-04 US disclosed
US-4072807-A OLEFIN DISPROPORTIONATION CATALYST PHILLIPS PETROLEUM COMPANY (US) 1978-02-07 US disclosed
US-4049616-A Preparation of graft, block and crosslinked unsaturated polymers and copolymers by olefin metathesis THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-09-20 US disclosed
US-4010224-A Preparation of graft, block and crosslinked unsaturated polymers and copolymers by olefin metathesis THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-03-01 US disclosed
US-4010217-A NITROSYL MOLYBDENUM OR TUNGSTEN COORDINATION CATALYST, ORGANOALUMINUM ADJUVANT PHILLIPS PETROLEUM COMPANY (US) 1977-03-01 US disclosed
US-3995095-A Modification of polymers by treatment with olefins PHILLIPS PETROLEUM COMPANY (US) 1976-11-30 US disclosed
US-3981940-A SUPPORTED MOLYBDENUM OXIDE OR TUNGSTEN OXIDE CATALYST PHILLIPS PETROLEUM COMPANY (US) 1976-09-21 US disclosed
US-3940346-A DISPROPORTIONATION PHILLIPS PETROLEUM COMPANY (US) 1976-02-24 US disclosed
US-3935270-A Process for the preparation of cyclohexadecenones and derivatives THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-01-27 US disclosed