Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 14/20 | 0.75 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889715 | 1.00 | FPR2 (0.75) | FPR2ANPEPALDH1A1LMNAMAPT | |
| SCHEMBL14889891 | 0.86 | FPR2 (0.56) | FPR2ANPEP | |
| SCHEMBL20484374 | 0.86 | FPR2 (0.56) | FPR2ANPEP | |
| SCHEMBL14902601 | 0.86 | FPR2 (1.00) | FPR2ANPEPALDH1A1LMNAMAPT | |
| SCHEMBL20484214 | 0.86 | FPR2 (1.00) | FPR2ANPEPALDH1A1LMNAMAPT | |
| SCHEMBL20484275 | 0.85 | FPR2 (0.64) | FPR2ANPEP | |
| SCHEMBL14902678 | 0.85 | FPR2 (0.64) | FPR2ANPEP | |
| SCHEMBL20983162 | 0.85 | FPR2 (0.74) | FPR2ANPEP | |
| SCHEMBL14889766 | 0.85 | FPR2 (0.74) | FPR2ANPEP | |
| SCHEMBL14889769 | 0.85 | FPR2 (0.74) | FPR2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964213-B1 | USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES | ALLERGAN INC (US) | 2020-11-04 | — | — | EP | claimed |
| EP-3078656-B1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2020-07-01 | — | — | EP | claimed |
| CN-105007909-B | Use of formyl peptide receptor 2 agonists for the treatment of ocular inflammatory diseases | 阿勒根公司 | 2019-06-28 | — | — | CN | claimed |
| CN-105007908-B | Use of agonists of formyl peptide receptor 2 for the treatment of skin diseases | 阿勒根公司 | 2017-10-03 | — | — | CN | claimed |
| CN-106518742-A | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2017-03-22 | — | — | CN | claimed |
| CN-104114164-A | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | ALLERGAN INC | 2014-10-22 | — | — | CN | claimed |
| EP-3795148-A1 | USE OF AGONISTS OF FORMYL PEPTIDE RECEPTOR 2 FOR TREATING OCULAR INFLAMMATORY DISEASES | ALLERGAN, INC. (US) | 2021-03-24 | — | — | EP | disclosed |
| EP-3078656-B1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2020-07-01 | — | — | EP | disclosed |
| CN-106518742-B | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2020-01-21 | — | — | CN | disclosed |
| EP-2770989-B1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2018-09-05 | — | — | EP | disclosed |
| CN-106518742-A | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-104114164-B | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | 阿勒根公司 | 2016-11-16 | — | — | CN | disclosed |
| CN-104114164-A | Amide derivatives of N-urea substituted amino acids as formyl peptide receptor-like-1 (FPRL-1) receptor modulators | ALLERGAN INC | 2014-10-22 | — | — | CN | disclosed |