SCHEMBL2048540

SCHEMBL2048540

CCC(C)c1cccc([O])c1C(C)CC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
HDAC4 P56524 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
RORC P51449 1/20 0.34
PKM P14618 1/20 0.34
GABRA1 P14867 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
NFKB1 P19838 1/20 0.33
RAB9A P51151 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ELANE P08246 1/20 0.33
KDM4E B2RXH2 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FAAH O00519 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2371854 0.87 TSHR (0.58) TSHRHDAC4HDAC2HDAC8RORC
SCHEMBL202737 0.82 TSHR (0.58) TSHRHDAC4HDAC2HDAC8RORC
SCHEMBL3087074 0.82 TSHR (0.48) TSHRHDAC4HDAC2HDAC8RORC
SCHEMBL395853 0.80 TSHR (0.61) TSHRHDAC4HDAC2HDAC8RORC
Ethylene SCHEMBL15018849 0.79 TSHR (0.66) TSHRHDAC4HDAC2HDAC8RORC
SCHEMBL2476981 0.78 TSHR (0.48) TSHRHDAC4HDAC2HDAC8RORC
SCHEMBL15914962 0.78 TSHR (0.48) TSHRHDAC4HDAC2HDAC8RORC
SCHEMBL10961181 0.78 TSHR (0.48) TSHRHDAC4HDAC2HDAC8RORC
SCHEMBL355986 0.78 TSHR (0.70) TSHRHDAC4HDAC2HDAC8RORC
SCHEMBL31330562 0.78 TSHR (0.70) TSHRHDAC4HDAC2HDAC8RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11639414-B2 Water-based polyurethane resin and manufacturing method thereof NAN YA PLASTICS CORPORATION (TW) 2023-05-02 US disclosed
US-20220127406-A1 WATER-BASED POLYURETHANE RESIN AND MANUFACTURING METHOD THEREOF NAN YA PLASTICS CORPORATION (TW) 2022-04-28 US disclosed
US-11254780-B2 Method for preparing aqueous polyurethane dispersion NAN YA PLASTICS CORPORATION (TW) 2022-02-22 US disclosed
US-20200325266-A1 METHOD FOR PREPARING AQUEOUS POLYURETHANE DISPERSION NAN YA PLASTICS CORPORATION (TW) 2020-10-15 US disclosed
US-8940363-B2 Preparation of hollow polymer microspheres NAN YA PLASTICS CORPORATION (TW) 2015-01-27 US disclosed
US-20140050845-A1 PREPARATION OF HOLLOW POLYMER MICROSPHERES NAN YA PLASTICS CORPORATION (TW) 2014-02-20 US disclosed
US-20110210322-A1 POLYMER COMPOUND CONTAINING NITROGEN-CONTAINING HETEROCYCLIC STRUCTURE, AND COMPOSITION, SOLUTION, THIN FILM AND POLYMER LIGHT-EMITTING ELEMENT EACH CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-01 US disclosed
EP-2336215-A1 POLYMER COMPOUND CONTAINING NITROGEN-CONTAINING HETEROCYCLIC STRUCTURE, AND COMPOSITION, SOLUTION, THIN FILM AND POLYMER LIGHT-EMITTING ELEMENT EACH CONTAINING SAME Sumitomo Chemical Company, Limited (JP) 2011-06-22 EP disclosed
US-20100010166-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2010-01-14 US disclosed
EP-2064256-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2009-06-03 EP disclosed
WO-2008031895-A1 SILANE-TERMINATED PREPOLYMERS AND RELATIVE ADHESIVE SEALANT FORMULATIONS N.P.T. S.R.L. (IT) 2008-03-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110210322-A1 POLYMER COMPOUND CONTAINING NITROGEN-CONTAINING HETEROCYCLIC STRUCTURE, AND COMPOSITION, SOLUTION, THIN FILM AND POLYMER LIGHT-EMITTING ELEMENT EACH CONTAINING SAME H1-10, RNF10, F10 TSHR 3961/4885HDAC4 1760/4885HDAC2 793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.