SCHEMBL3087074

SCHEMBL3087074

CCc1cccc(C(C)CC)c1C(C)CC

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
GABRA1 P14867 6/20 0.40
GABRB2 P47870 5/20 0.40
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HTT P42858 1/20 0.34
RORC P51449 1/20 0.33
PKM P14618 1/20 0.33
ELANE P08246 3/20 0.33
GABRG2 P18507 1/20 0.32
GABRB3 P28472 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2371854 0.85 TSHR (0.58) TSHRGABRA1GABRB2LMNAL3MBTL1
SCHEMBL2048540 0.82 TSHR (0.50) TSHRGABRA1GABRB2LMNASMN1; SMN2
SCHEMBL3627333 0.81 TSHR (0.59) TSHRGABRA1GABRB2L3MBTL1HTT
SCHEMBL1314427 0.80 TSHR (0.42) TSHRGABRA1GABRB2L3MBTL1HTT
SCHEMBL9579244 0.80 TSHR (0.48) TSHRGABRA1GABRB2HDAC4HDAC2
SCHEMBL10486191 0.78 GABRA1 (0.59) TSHRGABRA1GABRB2LMNAHDAC4
SCHEMBL22526089 0.78 TSHR (0.47) TSHRGABRA1GABRB2HDAC4HDAC2
SCHEMBL398716 0.78 TSHR (0.47) TSHRGABRA1GABRB2HDAC4HDAC2
SCHEMBL9838740 0.77 TSHR (0.59) TSHRGABRA1GABRB2L3MBTL1HTT
SCHEMBL202737 0.76 TSHR (0.58) TSHRGABRA1GABRB2LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107533878-B Electric insulating oil base oil for oil-filled electrical equipment, electric insulating oil containing same, and oil-filled electrical equipment 日新电机株式会社 2020-03-10 CN disclosed
US-8502002-B2 Microscope immersion oil IDEMITSU KOSAN CO., LTD. (JP) 2013-08-06 US disclosed
EP-2048193-B1 MICROSCOPE IMMERSION OIL IDEMITSU KOSAN CO (JP) 2012-09-05 EP disclosed
US-20100224833-A1 MICROSCOPE IMMERSION OIL IDEMITSU KOSAN CO. LTD (JP) 2010-09-09 US disclosed
EP-2048193-A1 MICROSCOPE IMMERSION OIL Idemitsu Kosan Co., Ltd. (JP) 2009-04-15 EP disclosed