Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELOVL1 | Q9BW60 | 6/20 | 0.77 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.61 |
| ▸ | CACNA1I | Q9P0X4 | 4/20 | 0.61 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20249743 | 0.93 | ELOVL1 (0.77) | ELOVL1CACNA1GCACNA1ICACNA1HMAPT | |
| SCHEMBL20485402 | 0.90 | ELOVL1 (0.76) | ELOVL1CACNA1GCACNA1ICACNA1HMAPT | |
| SCHEMBL18320907 | 0.87 | ELOVL1 (1.00) | ELOVL1CACNA1GCACNA1ICACNA1HMAPT | |
| SCHEMBL20485270 | 0.86 | ELOVL1 (0.82) | ELOVL1CACNA1GCACNA1ICACNA1HMAPT | |
| SCHEMBL20250000 | 0.86 | ELOVL1 (0.82) | ELOVL1CACNA1GCACNA1ICACNA1HMAPT | |
| SCHEMBL20485356 | 0.86 | ELOVL1 (0.73) | ELOVL1CACNA1GCACNA1ICACNA1HMAPT | |
| SCHEMBL20250059 | 0.86 | ELOVL1 (0.77) | ELOVL1CACNA1GCACNA1ICACNA1HMAPT | |
| SCHEMBL20485290 | 0.86 | ELOVL1 (0.77) | ELOVL1CACNA1GCACNA1ICACNA1HMAPT | |
| SCHEMBL20485374 | 0.85 | ELOVL1 (0.72) | ELOVL1CACNA1GCACNA1ICACNA1HMAPT | |
| SCHEMBL20249941 | 0.84 | ELOVL1 (0.74) | ELOVL1CACNA1GCACNA1ICACNA1HMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180251431-A1 | 1,3-SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL FOR REDUCTION OF VERY LONG CHAIN FATTY ACID LEVELS | VERTEX PHARMACEUTICALS INCORPORATED | 2018-09-06 | — | — | US | claimed |
| US-20180251431-A1 | 1,3-SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL FOR REDUCTION OF VERY LONG CHAIN FATTY ACID LEVELS | VERTEX PHARMACEUTICALS INCORPORATED | 2018-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180251431-A1 | 1,3-SUBSTITUTED PYRAZOLE COMPOUNDS USEFUL FOR REDUCTION OF VERY LONG CHAIN FATTY ACID LEVELS | HSD17B4, CPT1A, ADH1A | ELOVL1 39/4885CACNA1G 2851/4885CACNA1I 2448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.