Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.55 |
| ▸ | CA2 | P00918 | 14/20 | 0.55 |
| ▸ | CA9 | Q16790 | 5/20 | 0.55 |
| ▸ | CA4 | P22748 | 5/20 | 0.55 |
| ▸ | CA12 | O43570 | 5/20 | 0.55 |
| ▸ | CA7 | P43166 | 5/20 | 0.55 |
| ▸ | CA6 | P23280 | 4/20 | 0.55 |
| ▸ | CA5A | P35218 | 4/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.55 |
| ▸ | CA3 | P07451 | 3/20 | 0.55 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1699945 | 0.89 | CA1 (0.57) | CA1CA2CA9CA4CA12 | |
| SCHEMBL2777246 | 0.87 | CA2 (0.46) | CA1CA2CA9CA4CA12 | |
| SCHEMBL2777121 | 0.87 | CA2 (0.46) | CA1CA2CA9CA4CA12 | |
| SCHEMBL5014186 | 0.86 | CA1 (0.70) | CA1CA2CA9CA4CA12 | |
| SCHEMBL2777644 | 0.84 | CA1 (0.47) | CA1CA2CA9CA4CA12 | |
| SCHEMBL11554954 | 0.83 | CA1 (0.62) | CA1CA2CA9CA4CA12 | |
| SCHEMBL3778122 | 0.83 | CA1 (0.62) | CA1CA2CA9CA4CA12 | |
| SCHEMBL20485787 | 0.82 | CA1 (0.50) | CA1CA2CA9CA4CA12 | |
| SCHEMBL11552993 | 0.82 | CA1 (0.55) | CA1CA2CA9CA4CA12 | |
| SCHEMBL6038485 | 0.81 | CA1 (0.64) | CA1CA2CA9CA4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10316026-B2 | Method for removing dimethoxybenzyl group | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2019-06-11 | — | — | US | disclosed |
| EP-3372583-A1 | METHOD FOR REMOVING DIMETHOXYBENZYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-09-12 | — | — | EP | disclosed |
| US-20180251448-A1 | METHOD FOR REMOVING DIMETHOXYBENZYL GROUP | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2018-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180251448-A1 | METHOD FOR REMOVING DIMETHOXYBENZYL GROUP | DDT, ALKBH5, DDO | CA1 2756/4885CA2 3283/4885CA9 716/4885 |
| US-10316026-B2 | Method for removing dimethoxybenzyl group | DDT, ALKBH5, DDO | CA1 2756/4885CA2 3283/4885CA9 716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.