Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20487800 | 0.74 | MEN1 (0.33) | DRD3 | |
| SCHEMBL20487813 | 0.74 | FPR2 (0.30) | — | |
| SCHEMBL24954123 | 0.70 | TRPA1 (0.35) | — | |
| SCHEMBL24625919 | 0.70 | TRPA1 (0.40) | — | |
| SCHEMBL20487799 | 0.69 | — | — | |
| SCHEMBL20487822 | 0.69 | DDB1 (0.33) | MAPK1 | |
| SCHEMBL20488157 | 0.69 | DDB1 (0.33) | MAPK1 | |
| SCHEMBL22663506 | 0.62 | PRMT5 (0.40) | BRD4 | |
| SCHEMBL15695732 | 0.60 | MGAM (0.33) | — | |
| SCHEMBL12889366 | 0.60 | MGAM (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018160824-A1 | SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5) | PRELUDE THERAPEUTICS, INCORPORATED (US) | 2018-09-07 | — | — | WO | disclosed |