Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ESRRB | O95718 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25076475 | 1.00 | ABCB1 (0.52) | ABCB1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27175581 | 0.85 | KMT2A (0.59) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL10321592 | 0.79 | ABCB1 (0.56) | ABCB1ALDH1A1KDM4ETDP1CHRM2 | |
| SCHEMBL10320993 | 0.79 | ABCB1 (0.56) | ABCB1ALDH1A1KDM4ETDP1CHRM2 | |
| SCHEMBL25076539 | 0.76 | KMT2A (0.61) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL16825792 | 0.74 | DRD2 (0.53) | ABCB1ALDH1A1KDM4EESRRBESR1 | |
| SCHEMBL16846206 | 0.74 | DRD2 (0.53) | ABCB1ALDH1A1KDM4EESRRBESR1 | |
| SCHEMBL16846231 | 0.74 | DRD2 (0.53) | ABCB1ALDH1A1KDM4EESRRBESR1 | |
| SCHEMBL608201 | 0.73 | MEN1 (0.64) | ABCB1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL606958 | 0.73 | MEN1 (0.64) | ABCB1ALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387447-A1 | COMPOSITIONS FOR ORGAN AND TISSUE PRESERVATION | Albert Einstein College of Medicine (US) | 2024-06-26 | — | — | EP | disclosed |
| WO-2023023316-A1 | COMPOSITIONS FOR ORGAN AND TISSUE PRESERVATION | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2023-02-23 | — | — | WO | disclosed |
| WO-2018165494-A1 | SMALL MOLECULE BAX INHIBITORS AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (US) | 2018-09-13 | — | — | WO | disclosed |