Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | BAX | Q07812 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25076580 | 0.95 | BAX (0.53) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL25076578 | 0.87 | KMT2A (0.61) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL25076581 | 0.85 | MEN1 (0.42) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL27175581 | 0.82 | KMT2A (0.59) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL25076575 | 0.81 | KMT2A (0.52) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL25076572 | 0.79 | SIGMAR1 (0.43) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL25076475 | 0.76 | ABCB1 (0.52) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL20495152 | 0.76 | ABCB1 (0.52) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL5551349 | 0.72 | DNM1 (0.54) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL5557210 | 0.71 | RAD52 (0.51) | KMT2AALDH1A1MEN1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250134095-A1 | COMPOSITIONS FOR ORGAN AND TISSUE PRESERVATION | ALBERT EINSTEIN COLLEGE MEDICINE (US) | 2025-05-01 | — | — | US | disclosed |
| US-20250000857-A1 | SMALL MOLECULE BAX INHIBITORS AND USES THEREOF | ALBERT EINSTEIN COLLEGE MEDICINE (US) | 2025-01-02 | — | — | US | disclosed |
| US-20240350482-A1 | SMALL MOLECULE BAX INHIBITORS AND USES THEREOF | THE UNIVERSITY OF MANITOBA (CA) | 2024-10-24 | — | — | US | disclosed |
| EP-4387447-A1 | COMPOSITIONS FOR ORGAN AND TISSUE PRESERVATION | Albert Einstein College of Medicine (US) | 2024-06-26 | — | — | EP | disclosed |
| US-11938128-B2 | Small molecule BAX inhibitors and uses thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2024-03-26 | — | — | US | disclosed |
| WO-2023023316-A1 | COMPOSITIONS FOR ORGAN AND TISSUE PRESERVATION | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2023-02-23 | — | — | WO | disclosed |
| WO-2023023316-A1 | COMPOSITIONS FOR ORGAN AND TISSUE PRESERVATION | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2023-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250000857-A1 | SMALL MOLECULE BAX INHIBITORS AND USES THEREOF | BAX, BCL2, BAK1 | KMT2A 4375/4885ALDH1A1 3876/4885MEN1 2798/4885 |
| US-20250134095-A1 | COMPOSITIONS FOR ORGAN AND TISSUE PRESERVATION | PIGS, ALPG, ALPP | KMT2A 4811/4885ALDH1A1 1110/4885MEN1 2626/4885 |
| US-11938128-B2 | Small molecule BAX inhibitors and uses thereof | BAX, BCL2, TMBIM6 | KMT2A 4640/4885ALDH1A1 4302/4885MEN1 2920/4885 |
| US-20240350482-A1 | SMALL MOLECULE BAX INHIBITORS AND USES THEREOF | BAX, BCL2, TMBIM6 | KMT2A 4640/4885ALDH1A1 4302/4885MEN1 2920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.