Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20495279 | 1.00 | PPARG (0.38) | PPARGTBXA2RAGTR1AGTR2ALOX5AP | |
| Hydrochloric Acid SCHEMBL20494952 | 0.99 | PPARG (0.38) | PPARGTBXA2RAGTR1AGTR2ALOX5AP | |
| Hydrochloric Acid SCHEMBL20494951 | 0.98 | PPARG (0.37) | PPARGTBXA2RAGTR1AGTR2ALOX5AP | |
| SCHEMBL21973157 | 0.96 | PPARG (0.40) | PPARGALOX5APPOLBGNRHRS1PR3 | |
| Hydrochloric Acid SCHEMBL20495222 | 0.95 | PPARG (0.40) | PPARGALOX5APPOLBGNRHRS1PR3 | |
| Hydrochloric Acid SCHEMBL20495220 | 0.95 | PPARG (0.40) | PPARGALOX5APPOLBGNRHRS1PR3 | |
| SCHEMBL20495074 | 0.93 | RORC (0.37) | AGTR1AGTR2MEN1ALDH1A1HPGD | |
| SCHEMBL20495075 | 0.93 | RORC (0.37) | AGTR1AGTR2MEN1ALDH1A1HPGD | |
| SCHEMBL20494828 | 0.89 | S1PR3 (0.39) | POLBS1PR3 | |
| SCHEMBL21973633 | 0.89 | S1PR3 (0.41) | ALOX5APS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180459-B2 | Bacterial efflux pump inhibitors | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200140393-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERISTY OF NEW JERSEY (US) | 2020-05-07 | — | — | US | disclosed |
| WO-2018165612-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180459-B2 | Bacterial efflux pump inhibitors | ABCB11, ABCB1, SLC47A1 | PPARG 3051/4885TBXA2R 2585/4885AGTR1 1572/4885 |
| US-20200140393-A1 | BACTERIAL EFFLUX PUMP INHIBITORS | ABCB11, ABCB1, SLC47A1 | PPARG 3051/4885TBXA2R 2585/4885AGTR1 1572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.