Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18870066 | 0.84 | HPGD (0.55) | HPGDRAB9ACYP3A4CYP2C19SCN3A | |
| SCHEMBL2049574 | 0.81 | HPGD (0.59) | HPGDRAB9ACYP3A4CYP2C19SCN3A | |
| SCHEMBL28078351 | 0.80 | LMNA (0.48) | HPGDRAB9ACYP3A4CYP2C19SCN3A | |
| SCHEMBL28181525 | 0.80 | HPGD (0.58) | HPGDRAB9ACYP3A4CYP2C19SCN3A | |
| SCHEMBL13998890 | 0.80 | HPGD (0.62) | HPGDRAB9ACYP3A4CYP2C19SCN3A | |
| SCHEMBL11484603 | 0.79 | FFAR1 (0.53) | HPGDRAB9ACYP3A4CYP2C19SCN3A | |
| SCHEMBL1149358 | 0.79 | FFAR1 (0.53) | HPGDRAB9ACYP3A4CYP2C19SCN3A | |
| SCHEMBL1149769 | 0.79 | FFAR1 (0.53) | HPGDRAB9ACYP3A4CYP2C19SCN3A | |
| SCHEMBL18815137 | 0.77 | ALDH1A1 (0.60) | HPGDRAB9ACYP3A4CYP2C19SCN3A | |
| Acetic Acid SCHEMBL159740 | 0.77 | FFAR1 (0.66) | HPGDRAB9ACYP3A4CYP2C19SCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168642-B2 | Dihydropyrimidine compounds and their uses in preparation of medicaments for treating and preventing antiviral diseases | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2012-05-01 | — | — | US | disclosed |
| EP-2336115-A1 | Dihydropyrimidine compounds and use thereof for the treatment of viral diseases | Beijing Molecule Science and Technology Co., Ltd. (CN) | 2011-06-22 | — | — | EP | disclosed |
| US-20100087448-A1 | Dihydropyrimidine Compounds and Their Uses in Preparation of Medicaments for Treating and Preventing Antiviral Diseases | BEIJING MOLECULE SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2010-04-08 | — | — | US | disclosed |
| EP-2039686-A1 | DIHYDROPYRIMIDINE COMPOUNDS AND THEIR USES IN PREPARATION OF MEDICAMENTS FOR TREATING AND PREVENTING ANTIVIRAL DISEASES | Beijing Molecule Science and Technology Co., Ltd. (CN) | 2009-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087448-A1 | Dihydropyrimidine Compounds and Their Uses in Preparation of Medicaments for Treating and Preventing Antiviral Diseases | DPYD, HPRT1, DHX15 | HPGD 303/4885RAB9A 2568/4885CYP3A4 662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.