SCHEMBL20496972

SCHEMBL20496972

CCCCCCc1c(C(=O)ON(CC)CC)cccc1C(=O)c1cccc(O)c1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BID P55957 3/20 0.41
MCL1 Q07820 3/20 0.41
KAT8 Q9H7Z6 3/20 0.41
BCL2L1 Q07817 2/20 0.41
BAK1 Q16611 2/20 0.41
EP300 Q09472 2/20 0.41
KAT5 Q92993 2/20 0.41
SAE1 Q9UBE0 2/20 0.41
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
KAT2A Q92830 1/20 0.41
KAT2B Q92831 1/20 0.41
IAPP P10997 1/20 0.39
CNR1 P21554 2/20 0.38
CNR2 P34972 2/20 0.38
MMP2 P08253 2/20 0.37
F7 P08709 2/20 0.37
F3 P13726 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL101784 0.92 BID (0.42) BIDMCL1KAT8BCL2L1BAK1
Hydrochloric Acid SCHEMBL1276007 0.91 BID (0.41) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL23779420 0.88 BID (0.47) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL3807359 0.84 NAAA (0.41) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL28790813 0.84 PTPN1 (0.41) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL27842727 0.82 KAT8 (0.40) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL4257038 0.81 NAAA (0.43) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL1923190 0.81 NAAA (0.43) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL28524989 0.79 ALOX5 (0.50) BIDMCL1KAT8BCL2L1BAK1
SCHEMBL995527 0.79 BID (0.43) BIDMCL1KAT8BCL2L1BAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11723856-B2 Use of UV resistant active materials on hair COAST SOUTHWEST INC. (US) 2023-08-15 US disclosed
US-20210045994-A1 USE OF UV RESISTANT ACTIVE MATERIALS ON HAIR COAST SOUTHWEST INC. 2021-02-18 US disclosed
US-10835481-B2 Use of UV resistant active materials on hair COAST SOUTHWEST, INC. (US) 2020-11-17 US disclosed
WO-2018170439-A1 USE OF UV RESISTANT ACTIVE MATERIALS ON HAIR COAST SOUTHWEST, INC. (US) 2018-09-20 WO disclosed
US-20180263891-A1 USE OF UV RESISTANT ACTIVE MATERIALS ON HAIR COAST SOUTHWEST INC. 2018-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180263891-A1 USE OF UV RESISTANT ACTIVE MATERIALS ON HAIR UNG, ERCC4, XPA BID 3826/4885MCL1 2932/4885KAT8 2508/4885
US-10835481-B2 Use of UV resistant active materials on hair UNG, ERCC4, XPA BID 3826/4885MCL1 2932/4885KAT8 2508/4885
US-20210045994-A1 USE OF UV RESISTANT ACTIVE MATERIALS ON HAIR UNG, ERCC4, XPA BID 4085/4885MCL1 3221/4885KAT8 2347/4885
US-11723856-B2 Use of UV resistant active materials on hair UNG, ERCC4, XPA BID 4085/4885MCL1 3221/4885KAT8 2347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.