Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.58 |
| ▸ | MDK | P21741 | 4/20 | 0.56 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.52 |
| ▸ | FGF1 | P05230 | 1/20 | 0.52 |
| ▸ | FGF2 | P09038 | 1/20 | 0.52 |
| ▸ | VEGFA | P15692 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | IDE | P14735 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HLCS | P50747 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20280629 | 1.00 | TDP1 (0.58) | TDP1MDKHPSEFGF1FGF2 | |
| Biotin SCHEMBL1270496 | 0.85 | TDP1 (0.61) | TDP1MDKHPSEFGF1FGF2 | |
| Biotin SCHEMBL2510950 | 0.85 | TDP1 (0.61) | TDP1MDKHPSEFGF1FGF2 | |
| SCHEMBL16264872 | 0.82 | MDK (0.75) | TDP1MDKHPSEFGF1FGF2 | |
| SCHEMBL18653674 | 0.82 | MDK (0.75) | TDP1MDKHPSEFGF1FGF2 | |
| SCHEMBL17727882 | 0.77 | TDP1 (0.67) | TDP1HPSEFGF1FGF2VEGFA | |
| SCHEMBL27849533 | 0.76 | TDP1 (0.56) | TDP1HPSEFGF1FGF2VEGFA | |
| Biotin SCHEMBL1270776 | 0.75 | TDP1 (0.72) | TDP1MDKHPSEFGF1FGF2 | |
| SCHEMBL10047674 | 0.75 | TDP1 (1.00) | TDP1HPSEMAPK1MEN1ABL1 | |
| SCHEMBL20844951 | 0.75 | TDP1 (1.00) | TDP1HPSEMAPK1MEN1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018169954-A1 | LIPID-BASED NANOPARTICLES WITH ENHANCED STABILITY | SDG, INC. (US) | 2018-09-20 | — | — | WO | claimed |