Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDK | P21741 | 4/20 | 0.75 |
| ▸ | FGF1 | P05230 | 1/20 | 0.57 |
| ▸ | FGF2 | P09038 | 1/20 | 0.57 |
| ▸ | VEGFA | P15692 | 1/20 | 0.57 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16264872 | 1.00 | MDK (0.75) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL20500199 | 0.82 | TDP1 (0.58) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL20280629 | 0.82 | TDP1 (0.58) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL19069484 | 0.82 | F2 (0.70) | MDKF2PRSS1PRSS2PRSS3 | |
| SCHEMBL9898618 | 0.81 | MDK (0.65) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL9898615 | 0.81 | MDK (0.65) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL9898612 | 0.81 | MDK (0.65) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL29442598 | 0.81 | MDK (0.68) | MDKFGF1FGF2VEGFAHPSE | |
| SCHEMBL27015699 | 0.81 | F2 (0.69) | MDKF2PRSS1PRSS2PRSS3 | |
| SCHEMBL19017236 | 0.81 | F2 (0.73) | F2PRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968624-B2 | Depression treatment agent | THE UNIVERSITY OF TOKYO (JP) | 2018-05-15 | — | — | US | disclosed |
| US-20180085385-A1 | GLUCOSE-SENSITIVE CELL PROTECTING AGENT | THE UNIVERSITY OF TOKYO (JP) | 2018-03-29 | — | — | US | disclosed |
| US-20170080004-A1 | DEPRESSION TREATMENT AGENT | THE UNIVERSITY OF TOKYO (JP) | 2017-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170080004-A1 | DEPRESSION TREATMENT AGENT | FUT6, FUT5, B3GNT2 | MDK 1490/4885FGF1 3349/4885FGF2 2927/4885 |
| US-20180085385-A1 | GLUCOSE-SENSITIVE CELL PROTECTING AGENT | FUT6, SLC2A3, B3GNT2 | MDK 1869/4885FGF1 2513/4885FGF2 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.