Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 7/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | TGM2 | P21980 | 5/20 | 0.46 |
| ▸ | F13A1 | P00488 | 4/20 | 0.46 |
| ▸ | TGM1 | P22735 | 4/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | TGM6 | O95932 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20500383 | 0.82 | TSHR (0.47) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL20500415 | 0.81 | CKS1B (0.48) | CTSKCNR1CNR2JAK2JAK1 | |
| SCHEMBL459989 | 0.75 | ALDH1A1 (0.56) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL20500350 | 0.75 | SSTR2 (0.40) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL6190799 | 0.75 | ALDH1A1 (0.58) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL30078473 | 0.75 | TGM2 (0.46) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL20500388 | 0.74 | CNR1 (0.43) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL1223261 | 0.74 | ALDH1A1 (0.45) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL17592966 | 0.73 | TSHR (0.63) | TSHRALDH1A1GAACTSLCTSB | |
| SCHEMBL21855497 | 0.73 | CA1 (0.63) | TSHRALDH1A1GAACTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11072598-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2021-07-27 | — | — | US | disclosed |
| WO-2018170284-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2018-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11072598-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | TSHR 70/4885ALDH1A1 4626/4885GAA 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.