Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.51 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20556495 | 1.00 | FAAH (0.57) | FAAHMEN1KMT2AMAPK1PLA2G2A | |
| SCHEMBL20556506 | 1.00 | FAAH (0.57) | FAAHMEN1KMT2AMAPK1PLA2G2A | |
| SCHEMBL9830996 | 0.89 | FAAH (0.50) | FAAHMEN1KMT2AMAPK1PLA2G2A | |
| SCHEMBL9830986 | 0.89 | FAAH (0.50) | FAAHMEN1KMT2AMAPK1PLA2G2A | |
| SCHEMBL25637739 | 0.87 | PLA2G10 (0.50) | FAAHMEN1KMT2AMAPK1PLA2G2A | |
| SCHEMBL26693629 | 0.87 | ALDH1A1 (0.48) | FAAHMEN1KMT2AMAPK1PLA2G2A | |
| SCHEMBL20556344 | 0.86 | PLA2G10 (0.57) | FAAHMEN1KMT2AMAPK1PLA2G2A | |
| SCHEMBL20556137 | 0.86 | PLA2G10 (0.57) | FAAHMEN1KMT2AMAPK1PLA2G2A | |
| SCHEMBL20556138 | 0.86 | PLA2G10 (0.57) | FAAHMEN1KMT2AMAPK1PLA2G2A | |
| SCHEMBL24095722 | 0.85 | FAAH (0.62) | FAAHMEN1KMT2AMAPK1PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377473-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2024-06-19 | — | — | EP | disclosed |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2023-05-04 | — | — | US | disclosed |
| CN-108884058-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2022-04-29 | — | — | CN | disclosed |
| US-20180327367-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | WUXI APPTEC CO., LTD (CN) | 2018-11-15 | — | — | US | disclosed |
| EP-3377473-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180327367-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | FAAH 3193/4885MEN1 2531/4885KMT2A 3283/4885 |
| US-20230133817-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | FAAH 3193/4885MEN1 2531/4885KMT2A 3283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.