Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20556573 | 0.85 | MAPT (0.46) | PTGS2CXCR1CXCR2ENPP3ALPL | |
| SCHEMBL4298023 | 0.79 | ALDH1A1 (0.59) | ALKBH1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL6052147 | 0.78 | MEN1 (0.53) | ALKBH1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL6052366 | 0.78 | NOTUM (0.49) | LMNAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL6052337 | 0.78 | NOTUM (0.49) | ALKBH1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL6052367 | 0.75 | L3MBTL1 (0.63) | ALKBH1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL29333627 | 0.74 | ALDH1A1 (0.42) | ALKBH1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL15167860 | 0.74 | CA12 (0.63) | PTGS2PTGS1LMNAALDH1A1MAPT | |
| SCHEMBL20552556 | 0.71 | ALDH1A1 (0.44) | ALKBH1LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL10321717 | 0.71 | ALDH1A1 (0.54) | LMNATSHRALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377473-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |